1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine

Base Information

• Chemical Name: 1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine
• CAS No.: 385843-92-5
• Molecular Formula: C₂₇H₃₂N₂O₂
• Molecular Weight: 416.563

Synonyms:1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine

Chemical Property of 1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine

Chemical Property:

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Technology Process of 1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine

There total 1 articles about 1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[4-(1-naphthyl)butyl]piperazine dihydrochloride → 1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine (385843-92-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In chloroform; for 3h; Heating;

DOI:10.1016/j.bmc.2006.12.039

Reference yield:

1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine (385843-92-5) + aqueous potassium hydroxide → 1-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-4-(4-naphthalen-1-yl-butyl)piperazine (385843-93-6)

Guidance literature:

With sodium borohydrid; In water;

Reference yield:

1-[2-(4-methoxyphenyl)-2-oxoethyl]-4-(4-naphthalen-1-yl-butyl)piperazine (385843-92-5) → 1-[2-(4-Methoxycarbonylphenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl-butyl)piperazine + 1-[2-(4-carbamoylphenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine (687997-79-1)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; hydrogenchloride; thionyl chloride;

Downstream raw materials:

1-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-4-(4-naphthalen-1-yl-butyl)piperazine

1-[2-(4-carbamoylphenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine

1-[2-(4-Fluorophenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine

1-[2-(3-carbamoylphenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine

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