4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol

Base Information

• Chemical Name: 4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol
• CAS No.: 173974-53-3
• Molecular Formula: C₂₃H₃₀Br₂O₂
• Molecular Weight: 498.298
• Mol file: 173974-53-3.mol

Synonyms:4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol

Chemical Property of 4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol

There total 1 articles about 4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,2'-dihydroxy-3,3'-di-tert-butyldiphenylmethane (133-63-1) → 4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol (173974-53-3)

Guidance literature:

With hydrogen bromide; In acetic acid; for 16h; Ambient temperature;

DOI:10.1021/jo9511197

Reference yield: 72.0%

2-bromo-6-(tert-butyl)phenol (23159-87-7) + 4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol (173974-53-3) → 4,4'-bis(3-bromo-4-hydroxy-5-tert-butylbenzyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol (173974-48-6)

Guidance literature:

at 80 ℃; for 8h;

DOI:10.1021/jo9511197

Reference yield:

4,4'-bis(bromomethyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol (173974-53-3) → 6,6'-di-tert-butyl-4,4'-bis(3-tert-butyl-4-hydroxybenzyl)-2,2'-methanediyldiphenol

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / 8 h / 80 °C

2: 69 percent / H₂, KOH / Raney Ni / methanol

With potassium hydroxide; hydrogen; nickel; In methanol;

DOI:10.1021/jo9511197

upstream raw materials:

formaldehyd

2,2'-dihydroxy-3,3'-di-tert-butyldiphenylmethane

Downstream raw materials:

4,4'-bis(3-bromo-4-hydroxy-5-tert-butylbenzyl)-6,6'-di-tert-butyl-2,2'-methanediyldiphenol