N-(4-Chlorophenyl)-2-hydroxybenzamide

Base Information

Chemical Name:N-(4-Chlorophenyl)-2-hydroxybenzamide
CAS No.:3679-63-8
Molecular Formula:C13H10ClNO2
Molecular Weight:247.681
Hs Code.:2924299090
NSC Number:63710,22902
DSSTox Substance ID:DTXSID8063129
Nikkaji Number:J308.165F
Wikidata:Q81990506
ChEMBL ID:CHEMBL397158
Mol file:3679-63-8.mol

Synonyms:N-(4-Chlorophenyl)-2-hydroxybenzamide;3679-63-8;4'-Chlorosalicylanilide;4'-Chloro-2-hydroxybenzanilide;Salicyl-4'-chloroanilide;Benzamide, N-(4-chlorophenyl)-2-hydroxy-;Salicylanilide, 4'-chloro-;o-Hydroxybenz-4-chloroanilide;o-Hydroxybenzo-4-chloranilide;N-(p-Chlorophenyl)salicylanilide;NSC 63710;NSC22902;NSC63710;NSC 22902;N-(4-chlorophenyl)-2-hydroxy-benzamide;N-(4-Chloro-phenyl)-2-hydroxy-benzamide;4'-chloro-salicylanilide;CHEMBL397158;SCHEMBL2698725;DTXSID8063129;BDBM234305;MFCD00020024;NSC-22902;NSC-63710;AKOS000211189;2-Hydroxybenzoyl-N-(4-chlorophenyl)amide;BS-17136;CS-0103030;N-(4-chlorophenyl)-2-hydroxybenzamide (6);D80947

Suppliers and Price of N-(4-Chlorophenyl)-2-hydroxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N-(4-chlorophenyl)-2-hydroxybenzamide AldrichCPR
250mg
$ 112.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
N-(4-Chloro-phenyl)-2-hydroxy-benzamide 95%+
5g
$ 978.75

Acints
N-(4-Chloro-phenyl)-2-hydroxy-benzamide 95%+
10g
$ 1732.75

Acints
N-(4-Chloro-phenyl)-2-hydroxy-benzamide 95%+
5g
$ 978.75

Acints
N-(4-Chloro-phenyl)-2-hydroxy-benzamide 95%+
1g
$ 282.75

Total 8 raw suppliers

Chemical Property of N-(4-Chlorophenyl)-2-hydroxybenzamide

Chemical Property:

Vapor Pressure:0.000148mmHg at 25°C
Melting Point:168-169 °C
Refractive Index:1.5270 (estimate)
Boiling Point:322.5°Cat760mmHg
PKA:8.27±0.30(Predicted)
Flash Point:148.8°C
PSA：49.33000
Density:1.386g/cm³
LogP:3.37090
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:12.1ug/L(temperature not stated)
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:247.0400063
Heavy Atom Count:17
Complexity:264

Purity/Quality:

95% ^*data from raw suppliers

N-(4-chlorophenyl)-2-hydroxybenzamide AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)Cl)O

Technology Process of N-(4-Chlorophenyl)-2-hydroxybenzamide

There total 9 articles about N-(4-Chlorophenyl)-2-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 104-12-1
p-chlorphenylisocyanate

: 108-95-2,27073-41-2
phenol

: 3679-63-8
4'-chlorosalicylanilide

Guidance literature:: boron trichloride; In toluene; for 16h; Heating;
DOI:10.1016/S0040-4020(01)87495-0

Reference yield: 87.0%

: 106-47-8
4-chloro-aniline

: 69-72-7,25496-36-0,8052-31-1
salicylic acid

: 3679-63-8
4'-chlorosalicylanilide

Guidance literature:: With phosphorus trichloride; In 5,5-dimethyl-1,3-cyclohexadiene; for 0.7h; Microwave irradiation;
DOI:10.1080/00397911.2010.481745

Reference yield: 67.0%

: 106-47-8
4-chloro-aniline

: 90-02-8
salicylaldehyde

: 3679-63-8
4'-chlorosalicylanilide

Guidance literature:: With [{(CH₂SiMe₂){(2,6-iPr₂C₆H₃)N}2}Y{N(SiMe₃)2}(THF)]; In toluene; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/ejoc.200901015