benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate

Base Information

Chemical Name:benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate
CAS No.:122250-32-2
Molecular Formula:C₂₆H₂₈N₂O₃
Molecular Weight:416.52
Hs Code.:

Synonyms:benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate

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Technology Process of benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate

There total 2 articles about benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5638-76-6
betahistine

: (R)-2-Benzyl-4-isobutoxycarbonyloxy-4-oxo-butyric acid benzyl ester

: 122250-32-2
benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate

Guidance literature:: With 4-methyl-morpholine; In dichloromethane; at -10 - 20 ℃; for 2.25h; Yield given;
DOI:10.1021/jm00056a006

Reference yield:

: 116129-80-7
(3R)-3-Benzyloxycarbonyl-3-phenylmethylpropionic acid

: 122250-32-2
benzyl (2R)-2-benzyl-3-<<(2-pyridin-2-ylethyl)methylamino>carbonyl>propionate

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / CH₂Cl₂ / 0.08 h / -10 °C

2: N-methylmorpholine / CH₂Cl₂ / 2.25 h / -10 - 20 °C

With 4-methyl-morpholine; In dichloromethane;
DOI:10.1021/jm00056a006