N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine

Base Information

• Chemical Name: N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine
• CAS No.: 121821-30-5
• Molecular Formula: C₄₁H₄₄N₄O₈S₂
• Molecular Weight: 784.954
• Mol file: 121821-30-5.mol

Synonyms:N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine

Chemical Property of N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine

There total 2 articles about N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-(4-bromobutyl)isoindoline-1,3-dione (5394-18-3) + N,N'-ditoluenesulfonyl-1,3-diaminopropane (53364-99-1) → N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine (121821-30-5)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; for 48h; Ambient temperature;

DOI:10.1246/bcsj.62.198

Reference yield:

phthalimide (136918-14-4,85-41-6) → N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine (121821-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent

2: 99 percent / Cs₂CO₃ / dimethylformamide / 48 h / Ambient temperature

With caesium carbonate; In N,N-dimethyl-formamide;

DOI:10.1246/bcsj.62.198

Reference yield: 92.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine (121821-30-5) → N,N'-bis(4-formamidobutyl)-N,N'-ditosyl-1,3-propanediamine (121821-17-8)

Guidance literature:

With hydrazine hydrate; at 75 ℃; for 23h;

DOI:10.1246/bcsj.62.198

upstream raw materials:

2-(4-bromobutyl)isoindoline-1,3-dione

N,N'-ditoluenesulfonyl-1,3-diaminopropane

phthalimide

Downstream raw materials:

N,N'-bis(4-formamidobutyl)-N,N'-ditosyl-1,3-propanediamine

N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine

4,9,13,18-tetratosyl-N¹,N²¹-diformyl-4,9,13,18-tetraazaheneicosane-1,21-diamine

4,9,13,18-tetratosyl-N¹,N¹:N²¹,N²¹-diphthaloyl-4,9,13,18-tetraazaheneicosane-1,21-diamine