4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

Base Information

Chemical Name:4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide
CAS No.:855481-78-6
Molecular Formula:C₂₂H₂₈BrNO₃
Molecular Weight:434.373
Hs Code.:

Synonyms:4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

Suppliers and Price of 4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

There total 2 articles about 4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₇H₁₈BrNO₂

: 24424-99-5
di-tert-butyl dicarbonate

: 855481-78-6
4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

Guidance literature:: C₁₇H₁₈BrNO₂; With dimethylsulfide borane complex; In tetrahydrofuran; at 20 ℃; for 0.5h; Heating / reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 10 - 20 ℃; for 3h;

di-tert-butyl dicarbonate; With sodium hydroxide; In tetrahydrofuran; water; at 10 - 20 ℃; for 1h; pH=7 - 8;

Reference yield:

: 1045705-38-1
C₁₇H₂₀BrNO

: 24424-99-5
di-tert-butyl dicarbonate

: 855481-78-6
4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 2h; pH=7 - 8;
DOI:10.1021/jm8000345

Reference yield:

: 855481-78-6
4-(2-{[(1S,2R)-2-hydroxy-2-phenyl-1-methylethyl]-tert-butyloxycarbonylamino}ethyl)phenylbromide

: 855482-81-4
[3-isobutyl-4-(methoxycarbonyl)phenyl]boronic acid

: 855478-01-2
Methyl 4'-[2-[(tert-butoxycarbonyl)[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-3-isobutyl-4-biphenylcarboxylate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 70 ℃; for 5h; Inert atmosphere;
DOI:10.1021/jm8000345