1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Base Information

Chemical Name:1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine
CAS No.:105281-15-0
Molecular Formula:C₁₈H₁₉FIN₃O₇S
Molecular Weight:567.334
Hs Code.:

Synonyms:1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Suppliers and Price of 1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

There total 3 articles about 1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 108-24-7
acetic anhydride

: 105281-00-3
Toluene-4-sulfonic acid (2R,3R,4S,5R)-5-(4-amino-5-iodo-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

: 105281-15-0
1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Guidance literature:: With pyridine; for 3h; Ambient temperature;
DOI:10.1021/jm00384a041

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 105281-15-0
1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 24 h / 4 °C

2: 85 percent / pyridine / 3 h / Ambient temperature

With pyridine;
DOI:10.1021/jm00384a041

Reference yield:

: 69123-90-6
fiacitabine

: 105281-15-0
1-(3-O-acetyl-2-deoxy-2-fluoro-5-O-tosyl-β-D-arabinofuranosyl)-5-iodocytosine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 24 h / 4 °C

2: 85 percent / pyridine / 3 h / Ambient temperature

With pyridine;
DOI:10.1021/jm00384a041