2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole

Base Information

• Chemical Name: 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole
• CAS No.: 1342801-42-6
• Molecular Formula: C₂₁H₂₀N₂O₂
• Molecular Weight: 332.402
• Mol file: 1342801-42-6.mol

Synonyms:2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole

Chemical Property of 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole

There total 3 articles about 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-tert-Butylbenzaldehyde (939-97-9) + furil (492-94-4) → 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole (1342801-42-6)

Guidance literature:

With ammonium acetate; In neat (no solvent); at 130 ℃; for 0.333333h; Microwave irradiation;

DOI:10.1515/chempap-2015-0014

Reference yield:

furfural (98-01-1) → 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole (1342801-42-6)

Guidance literature:

Multi-step reaction with 3 steps

1: vitamin B₁

2: copper diacetate

3: ammonium acetate; acetic acid

With ammonium acetate; vitamin B₁; copper diacetate; acetic acid; 3: Debus reaction;

DOI:10.1016/j.saa.2011.07.025

Reference yield:

furoin (552-86-3) → 2-(4-tert-butylphenyl)-4,5-di(2-furyl)-imidazole (1342801-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: copper diacetate

2: ammonium acetate; acetic acid

With ammonium acetate; copper diacetate; acetic acid; 2: Debus reaction;

DOI:10.1016/j.saa.2011.07.025

upstream raw materials:

furfural

4-tert-Butylbenzaldehyde

furil

furoin

Refernces

• 1、 Zhang, Jian,Zhao, Tian-Qi,Chen, Yaoz,Chen, Xiao-Dong,Chang, Hai-Kun,Zhang, Yu-Min,Hua, Shu-Cheng. "Microwave-assisted solvent-free synthesis and luminescence properties of 2-substituted-4,5-di(2-furyl)-1H-imidazoles". . p. 325 - 338. Retrieved 2015/02/19.