Taurolidine

Base Information Edit

Chemical Name:Taurolidine
CAS No.:19388-87-5
Molecular Formula:C7H16N4O4S2
Molecular Weight:284.36
Hs Code.:2933990090
European Community (EC) Number:243-016-5
UNII:8OBZ1M4V3V
DSSTox Substance ID:DTXSID00173001
Nikkaji Number:J9.698I
Wikipedia:Taurolidine
Wikidata:Q3981568
NCI Thesaurus Code:C2639
Metabolomics Workbench ID:153457
ChEMBL ID:CHEMBL2105420
Mol file:19388-87-5.mol

Synonyms:4,4'-methylenebis-(tetrahydro-1,2,4-thiadiazine- 1,1-dioxide);bis(1,1-dioxo-perhydro-1,2,4-thiadiazinyl-4)methane;bis- (1,1-dioxoperhydro-1,2,4-thiadiazinyl-4)methane;Tauroflex;taurolidine;Taurolin;Tauroline

Suppliers and Price of Taurolidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Taurolidine
1g
$ 346.00

TRC
Taurolidine
50mg
$ 145.00

Sigma-Aldrich
Taurolidine >97% (NMR), powder
5mg
$ 122.00

Sigma-Aldrich
Taurolidine >97% (NMR), powder
25mg
$ 457.00

Medical Isotopes, Inc.
Taurolidine
250 mg
$ 950.00

Crysdot
Taurolidin 97%
100g
$ 254.00

ChemScene
Taurolidine
10mg
$ 55.00

ChemScene
Taurolidine
100mg
$ 250.00

ChemScene
Taurolidine
50mg
$ 150.00

Chemenu
4,4''-methylenebis(1,2,4-thiadiazinane1,1-dioxide) 97%
1g
$ 316.00

Total 121 raw suppliers

Chemical Property of Taurolidine Edit

Chemical Property:

Vapor Pressure:4.74E-09mmHg at 25°C
Melting Point:156oC
Refractive Index:1.564
Boiling Point:471.214 °C at 760 mmHg
PKA:11.16±0.20(Predicted)
Flash Point:238.782 °C
PSA：115.58000
Density:1.467 g/cm³
LogP:0.02390
Storage Temp.:room temp
Solubility.:DMSO: >20mg/mL
XLogP3:-1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:284.06129735
Heavy Atom Count:17
Complexity:419

Purity/Quality:

99% ^*data from raw suppliers

Taurolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CS(=O)(=O)NCN1CN2CCS(=O)(=O)NC2
Recent ClinicalTrials:Taurolidine Containing Antimicrobial CIED Wash to Prevent Infection
Uses Taurolidine is a derivative of the amino acid Taurine (T007850). Taurolidine exhibits antiendotoxin and antimicrobial activity, and has also been shown to exhibit antitumour activity in vitro and in vivo. Taurolidine is used for the treatment of sepsis and is utilized in hospitals to prevent catheter-related bloodstream infections.

Technology Process of Taurolidine

There total 3 articles about Taurolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%