ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate

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Chemical Name:ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate
CAS No.:902473-25-0
Molecular Formula:C₂₂H₂₉F₃N₂O₅
Molecular Weight:458.478
Hs Code.:

Synonyms:ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate

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Chemical Property of ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate

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Technology Process of ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate

There total 1 articles about ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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: 902473-29-4
4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methyl-benzoic acid

: 902473-25-0
ethyl 4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methylbenzoylacetate

Guidance literature:: hydrogen ethyl malonate; With magnesium ethylate; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

4-[(3S,4S)-3-tertiary butoxycarbonylamino-4-fluoromethyl-1-pyrrolidinyl]-2,5-difluoro-3-methyl-benzoic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 0 - 20 ℃; for 18h;

With citric acid; In tetrahydrofuran; water; toluene; pH=2 - 3;