Technology Process of 2-(3-(1-Piperidinyl)propyl)-8,8-dipropyl-2-azaspiro(4.5)decane
There total 8 articles about 2-(3-(1-Piperidinyl)propyl)-8,8-dipropyl-2-azaspiro(4.5)decane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 98 percent / H2 / 10percent Pd/C / ethyl acetate / 5 h / 2585.7 Torr / Ambient temperature
2: 89 percent / ammonium acetate, acetic acid / toluene / Heating
3: ethanol; H2O / 5 h / Heating
4: acetic acid, hydrochloric acid, H2O / 84 h / Heating
5: 89 percent / acetic anhydride / 4 h / Heating
6: Heating
7: LiAlH4 / diethyl ether / 3 h
With
ammonium acetate; hydrogenchloride; lithium aluminium tetrahydride; water; hydrogen; acetic anhydride; acetic acid;
palladium on activated charcoal;
In
diethyl ether; ethanol; water; ethyl acetate; toluene;
DOI:10.1021/jm00173a010
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
diethyl ether;
for 3h;
Yield given;
DOI:10.1021/jm00173a010
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Heating
2: LiAlH4 / diethyl ether / 3 h
With
lithium aluminium tetrahydride;
In
diethyl ether;
DOI:10.1021/jm00173a010
