8,8-Dipropyl-2-oxaspiro[4.5]decane-1,3-dione

Base Information

Chemical Name:8,8-Dipropyl-2-oxaspiro[4.5]decane-1,3-dione
CAS No.:123018-64-4
Molecular Formula:C15H24O3
Molecular Weight:252.34926
Hs Code.:
DSSTox Substance ID:DTXSID50564541
Wikidata:Q82449269
Mol file:123018-64-4.mol

Synonyms:123018-64-4;8,8-DIPROPYL-2-OXASPIRO[4.5]DECANE-1,3-DIONE;8,8-DIPROPYL-2-OXA-SPIRO[4.5]DECANE-1,3-DIONE;DTXSID50564541

Suppliers and Price of 8,8-Dipropyl-2-oxaspiro[4.5]decane-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8,8-DIPROPYL-2-OXA-SPIRO[4.5]DECANE-1,3-DIONE 95.00%
5MG
$ 502.14

Total 2 raw suppliers

Chemical Property of 8,8-Dipropyl-2-oxaspiro[4.5]decane-1,3-dione

Chemical Property:

PSA：43.37000
LogP:3.60690
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:252.17254462
Heavy Atom Count:18
Complexity:330

Purity/Quality:

99% ^*data from raw suppliers

8,8-DIPROPYL-2-OXA-SPIRO[4.5]DECANE-1,3-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1(CCC2(CC1)CC(=O)OC2=O)CCC

Technology Process of 8,8-Dipropyl-2-oxaspiro[4.5]decane-1,3-dione

There total 5 articles about 8,8-Dipropyl-2-oxaspiro[4.5]decane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 130065-94-0
4,4-dipropyl-1-carboxycyclohexane-1-acetic acid

: 123018-64-4
4,4-dipropyl-1-carboxycyclohexane-1-acetic acid anhydride

Guidance literature:: With acetic anhydride; for 4h; Heating;
DOI:10.1021/jm00173a010

Reference yield:

: 60729-41-1
4,4-dipropylcyclohex-2-en-1-one

: 123018-64-4
4,4-dipropyl-1-carboxycyclohexane-1-acetic acid anhydride

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / H₂ / 10percent Pd/C / ethyl acetate / 5 h / 2585.7 Torr / Ambient temperature

2: 89 percent / ammonium acetate, acetic acid / toluene / Heating

3: ethanol; H₂O / 5 h / Heating

4: acetic acid, hydrochloric acid, H₂O / 84 h / Heating

5: 89 percent / acetic anhydride / 4 h / Heating

With ammonium acetate; hydrogenchloride; water; hydrogen; acetic anhydride; acetic acid; palladium on activated charcoal; In ethanol; water; ethyl acetate; toluene;
DOI:10.1021/jm00173a010

Reference yield:

: 123018-62-2
4,4-di-n-propylcyclohexanone

: 123018-64-4
4,4-dipropyl-1-carboxycyclohexane-1-acetic acid anhydride

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / ammonium acetate, acetic acid / toluene / Heating

2: ethanol; H₂O / 5 h / Heating

3: acetic acid, hydrochloric acid, H₂O / 84 h / Heating

4: 89 percent / acetic anhydride / 4 h / Heating

With ammonium acetate; hydrogenchloride; water; acetic anhydride; acetic acid; In ethanol; water; toluene;
DOI:10.1021/jm00173a010