Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate

Base Information

Chemical Name:Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate
CAS No.:79128-71-5
Molecular Formula:C₇H₉NO₄S₂
Molecular Weight:235.285
Hs Code.:2934999090
DSSTox Substance ID:DTXSID801203172
Nikkaji Number:J2.106.407F

Synonyms:Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate;79128-71-5;methyl 3-[(methylsulfonyl)amino]thiophene-2-carboxylate;methyl 3-(methanesulfonamido)thiophene-2-carboxylate;MFCD00126700;methyl 3-methanesulfonamidothiophene-2-carboxylate;Maybridge1_004604;Oprea1_158017;SCHEMBL17900443;HMS554J06;JDRDODRTERMXSR-UHFFFAOYSA-N;DTXSID801203172;AC6836;STL081071;AKOS003829815;9N-379S;SY026757;CS-0314545;A914379;Methyl3-(Methylsulfonamido)thiophene-2-carboxylate;Methyl 3-[(methylsulfonyl)amino]-2-thiophenecarboxylate;3-[(Methylsulfonyl)amino]thiophene-2-carboxylic acid methyl ester

Suppliers and Price of Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 3-(methylsulfonamido)thiophene-2-carboxylate
5 g
$ 784.00

Crysdot
Methyl3-(Methylsulfonamido)thiophene-2-carboxylate 95+%
5g
$ 329.00

Arctom
Methyl3-(Methylsulfonamido)thiophene-2-carboxylate ≥95%
5g
$ 328.00

AK Scientific
methyl3-[(methylsulfonyl)amino]thiophene-2-carboxylate
10g
$ 3600.00

AK Scientific
methyl3-[(methylsulfonyl)amino]thiophene-2-carboxylate
1g
$ 1200.00

AK Scientific
methyl3-[(methylsulfonyl)amino]thiophene-2-carboxylate
20mg
$ 267.00

Total 5 raw suppliers

Chemical Property of Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:234.99730012
Heavy Atom Count:14
Complexity:308

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-(methylsulfonamido)thiophene-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=C(C=CS1)NS(=O)(=O)C

Technology Process of Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate

There total 3 articles about Methyl 3-(Methylsulfonamido)thiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 124-63-0
methanesulfonyl chloride

: 79128-71-5
methyl 3-(methylsulfonamido)thiophene-2-carboxylate

Guidance literature:: In pyridine; at 50 ℃; for 1h; Inert atmosphere;
DOI:10.1002/chem.201303928

Reference yield: 86.0%

: 214532-29-3
methyl 3-(bis(methylsulfonyl)amino)-2-thiophenecarboxylate

: 79128-71-5
methyl 3-(methylsulfonamido)thiophene-2-carboxylate

Guidance literature:: With sodium methylate; In methanol; for 24h; Ambient temperature;
DOI:10.1002/jhet.5570350433

Reference yield:

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 79128-71-5
methyl 3-(methylsulfonamido)thiophene-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / Et₃N / tetrahydrofuran / Ambient temperature

2: 86 percent / NaOMe / methanol / 24 h / Ambient temperature

With sodium methylate; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1002/jhet.5570350433