7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

Base Information

Chemical Name:7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine
CAS No.:1453125-15-9
Molecular Formula:C₁₁H₈F₃N₇
Molecular Weight:295.227
Hs Code.:

Synonyms:7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

Suppliers and Price of 7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

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Technology Process of 7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

There total 3 articles about 7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 420-04-2
CYANAMID

: 16691-49-9
C₉H₈F₃N₅

: 122-51-0
orthoformic acid triethyl ester

: 1453125-15-9
7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

Guidance literature:: In methanol; at 150 ℃; for 0.333333h; regioselective reaction; Sealed tube; Microwave irradiation;
DOI:10.1016/j.tetlet.2013.07.158

Reference yield:

: 98-16-8
3-trifluoromethylaniline

: 1453125-15-9
7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 3 h / Reflux

2: hydrazine / ethanol / 3 h / Reflux

3: methanol / 0.33 h / 150 °C / Sealed tube; Microwave irradiation

With hydrazine; In methanol; ethanol;
DOI:10.1016/j.tetlet.2013.07.158

Reference yield:

: 61343-59-7
C₁₀H₈F₃N₃S

: 1453125-15-9
7-amino-2-(3-trifluoromethylphenylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / ethanol / 3 h / Reflux

2: methanol / 0.33 h / 150 °C / Sealed tube; Microwave irradiation

With hydrazine; In methanol; ethanol;
DOI:10.1016/j.tetlet.2013.07.158