(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Base Information

Chemical Name:(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol
CAS No.:1333237-20-9
Molecular Formula:C₃₃H₅₈Cl₄O₅Si₂
Molecular Weight:732.804
Hs Code.:

(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Synonyms:(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Suppliers and Price of (1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

There total 3 articles about (1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1333237-19-6
(2S,3R,6R,7R,8S,10S,11R)-3-(benzyloxy)-6,7,10,11-tetrachloro-11-((2S,3S)-3-(hydroxylmethyl)oxiran-2-yl)undecane-2,8-diol

: 69739-34-0
t-butyldimethylsiyl triflate

: 1333237-20-9
(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at -78 - -40 ℃; for 1.5h; Inert atmosphere;
DOI:10.1002/anie.201102521

Reference yield:

: 1333237-06-1
((2S,3S)-3-((1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-4,10-bis(tert-butyldimethylsilyloxy)-1,2,5,6-tetrachloroundecyl)oxiran-2-yl)methanol

: 1333237-20-9
(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; pyridine hydrofluoride / acetonitrile / 45 h / 0 - 20 °C / Inert atmosphere

2: 2,6-dimethylpyridine / dichloromethane / 1.5 h / -78 - -40 °C / Inert atmosphere

With pyridine; 2,6-dimethylpyridine; pyridine hydrofluoride; In dichloromethane; acetonitrile;
DOI:10.1002/anie.201102521

Reference yield:

: ((2S,3S)-3-((1R,2S,4S,9R,10S)-9-(benzyloxy)-4,10-bis(tert-butyldimethylsilyloxy)-1,2,5,6-tetrachloroundecyl)oxiran-2-yl)methyl acetate

: 1333237-20-9
(1R,2S,4S,5R,6R,9R,10S)-9-(benzyloxy)-10-(tert-butyldimethylsilyloxy)-1-((2S,3S)-3-((tert-butyldimethylsilyloxy)methyl)oxiran-2-yl)-1,2,5,6-tetrachloroundecan-4-ol

Guidance literature:: Multi-step reaction with 3 steps

1: methanol; potassium carbonate / 0.17 h / 0 °C / Inert atmosphere

2: pyridine; pyridine hydrofluoride / acetonitrile / 45 h / 0 - 20 °C / Inert atmosphere

3: 2,6-dimethylpyridine / dichloromethane / 1.5 h / -78 - -40 °C / Inert atmosphere

With pyridine; 2,6-dimethylpyridine; methanol; pyridine hydrofluoride; potassium carbonate; In dichloromethane; acetonitrile;
DOI:10.1002/anie.201102521