(2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Base Information

Chemical Name:(2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane
CAS No.:110205-99-7
Molecular Formula:C₂₇H₄₆N₄O₆S
Molecular Weight:554.751
Hs Code.:

(2R,3S)-3-<<N-(tert-butyloxycarbonyl)histidyl>amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Synonyms:(2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Suppliers and Price of (2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

There total 5 articles about (2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110206-10-5
(2R,3S)-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

: 17791-52-5
N-(tert-butoxycarbonyl)-L-histidine

: 110205-99-7
(2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Guidance literature:: With 4-methyl-morpholine; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at -23 - 20 ℃; Yield given;
DOI:10.1021/jm00394a035

Reference yield:

: 1569-69-3
Cyclohexanethiol

: 110205-99-7
(2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Guidance literature:: Multi-step reaction with 4 steps

1: 50 percent / triethylamine / methanol / 2 h / Heating

2: 97 percent / m-chloroperoxybenzoic acid / CH₂Cl₂ / 1 h

3: HCl / ethanol / Ambient temperature

4: 1-hydroxybenzotriazole monohydrate (HOBt), N-methylmorpholine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / dimethylformamide / -23 - 20 °C

With 4-methyl-morpholine; hydrogenchloride; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00394a035

Reference yield:

: 107202-61-9
(2R,3S)-3-(t-butoxycarbonylamino)-4-cyclohexyl-1,2-epoxybutane

: 110205-99-7
(2R,3S)-3-<amino>-4-cyclohexyl-1-(cyclohexylsulfonyl)-2-hydroxybutane

Guidance literature:: Multi-step reaction with 4 steps

1: 50 percent / triethylamine / methanol / 2 h / Heating

2: 97 percent / m-chloroperoxybenzoic acid / CH₂Cl₂ / 1 h

3: HCl / ethanol / Ambient temperature

4: 1-hydroxybenzotriazole monohydrate (HOBt), N-methylmorpholine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / dimethylformamide / -23 - 20 °C

With 4-methyl-morpholine; hydrogenchloride; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00394a035