phenyl-carbamic acid-[2]thienylmethyl ester

Base Information

• Chemical Name: phenyl-carbamic acid-[2]thienylmethyl ester
• CAS No.: 104294-31-7
• Molecular Formula: C₁₂H₁₁NO₂S
• Molecular Weight: 233.291
• Mol file: 104294-31-7.mol

Synonyms:phenyl-carbamic acid-[2]thienylmethyl ester

Chemical Property of phenyl-carbamic acid-[2]thienylmethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of phenyl-carbamic acid-[2]thienylmethyl ester

There total 3 articles about phenyl-carbamic acid-[2]thienylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Benzohydroxamic acid (495-18-1) + 2-thiophenemethanol (636-72-6) → phenyl-carbamic acid-[2]thienylmethyl ester (104294-31-7)

Guidance literature:

Benzohydroxamic acid; With 2-chloro-1,3-dimethylimidazolinium chloride; triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

(2-furyl)methyl alcohol; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1021/jo990211q

Reference yield:

thiophene-2-carbaldehyde (98-03-3) → phenyl-carbamic acid-[2]thienylmethyl ester (104294-31-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen; carbon monoxide; cobalt (II)-acetate tetrahydrate / 185 °C / 117681 Torr / in Hexan

With carbon monoxide; hydrogen; cobalt(II) acetate;

DOI:10.1021/ja01166a012

Reference yield:

2-thiophenemethanol (636-72-6) + phenyl isocyanate (103-71-9) → phenyl-carbamic acid-[2]thienylmethyl ester (104294-31-7)

Guidance literature:

DOI:10.1021/ja01166a012 DOI:10.1021/ja01216a040 DOI:10.1021/ja01590a053

upstream raw materials:

2-thiophenemethanol

phenyl isocyanate

thiophene-2-carbaldehyde

Benzohydroxamic acid

Downstream raw materials:

2-Methylthiophene