Eupomatenoid 5

Base Information

Chemical Name:Eupomatenoid 5
CAS No.:41744-28-9
Molecular Formula:C19H18O3
Molecular Weight:294.35
Hs Code.:
DSSTox Substance ID:DTXSID701317176
Nikkaji Number:J17.106I
ChEMBL ID:CHEMBL4565833
Mol file:41744-28-9.mol

Synonyms:eupomatenoid 5

Suppliers and Price of Eupomatenoid 5

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Eupomatenoid 5

Chemical Property:

Vapor Pressure:2.74E-08mmHg at 25°C
Boiling Point:438.2°Cat760mmHg
Flash Point:218.8°C
PSA：42.60000
Density:1.171g/cm³
LogP:5.15550
XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:294.125594432
Heavy Atom Count:22
Complexity:394

Purity/Quality:: ≥98% （HPLC） ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC=CC1=CC2=C(C=C1)OC(=C2C)C3=CC(=C(C=C3)O)OC
Isomeric SMILES:C/C=C/C1=CC2=C(C=C1)OC(=C2C)C3=CC(=C(C=C3)O)OC

Technology Process of Eupomatenoid 5

There total 16 articles about Eupomatenoid 5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64150-67-0
2,3,5-tribromobenzofuran

: 41744-28-9
eupomatenoid-5

Guidance literature:: Multi-step reaction with 4 steps

1.1: t-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C

1.2: ZnCl₂ / tetrahydrofuran; pentane / 0.17 h / -78 °C

1.3: 80 percent / [PdCl₂(PPh₃)2] / tetrahydrofuran; pentane / 6 h / 20 °C

2.1: [NiCl₂(dppe)] / tetrahydrofuran / 2 h / 20 °C

3.1: ZnCl₂ / tetrahydrofuran; diethyl ether / -78 °C

3.2: [PdCl₂(dppf)] / tetrahydrofuran; diethyl ether / 5 h / Heating

3.3: 72 percent / I₂ / tetrahydrofuran / 5 h / 20 °C / Irradiation

4.1: 95 percent / TBAF / tetrahydrofuran / 2 h / 20 °C

With tetrabutyl ammonium fluoride; tert.-butyl lithium; zinc(II) chloride; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; diethyl ether; pentane; 1.3: Negishi cross-coupling / 2.1: Kumada cross-coupling;

Reference yield:

: 149777-72-0
4-Bromo-2-methoxy-1-<(tert-butyldimethylsilyl)oxy>benzene

: 41744-28-9
eupomatenoid-5

Guidance literature:: Multi-step reaction with 4 steps

1.1: t-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C

1.2: ZnCl₂ / tetrahydrofuran; pentane / 0.17 h / -78 °C

1.3: 80 percent / [PdCl₂(PPh₃)2] / tetrahydrofuran; pentane / 6 h / 20 °C

2.1: [NiCl₂(dppe)] / tetrahydrofuran / 2 h / 20 °C

3.1: ZnCl₂ / tetrahydrofuran; diethyl ether / -78 °C

3.2: [PdCl₂(dppf)] / tetrahydrofuran; diethyl ether / 5 h / Heating

3.3: 72 percent / I₂ / tetrahydrofuran / 5 h / 20 °C / Irradiation

4.1: 95 percent / TBAF / tetrahydrofuran / 2 h / 20 °C

With tetrabutyl ammonium fluoride; tert.-butyl lithium; zinc(II) chloride; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; diethyl ether; pentane; 1.3: Negishi cross-coupling / 2.1: Kumada cross-coupling;

Reference yield:

: 489422-91-5
tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

: 41744-28-9
eupomatenoid-5

Guidance literature:: Multi-step reaction with 3 steps

1.1: [NiCl₂(dppe)] / tetrahydrofuran / 2 h / 20 °C

2.1: ZnCl₂ / tetrahydrofuran; diethyl ether / -78 °C

2.2: [PdCl₂(dppf)] / tetrahydrofuran; diethyl ether / 5 h / Heating

2.3: 72 percent / I₂ / tetrahydrofuran / 5 h / 20 °C / Irradiation

3.1: 95 percent / TBAF / tetrahydrofuran / 2 h / 20 °C

With tetrabutyl ammonium fluoride; zinc(II) chloride; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; diethyl ether; 1.1: Kumada cross-coupling;