tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Base Information

Chemical Name:tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane
CAS No.:489422-91-5
Molecular Formula:C₂₁H₂₄Br₂O₃Si
Molecular Weight:512.313
Hs Code.:

Synonyms:tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Suppliers and Price of tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

There total 4 articles about tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 64150-67-0
2,3,5-tribromobenzofuran

: 149777-72-0
4-Bromo-2-methoxy-1-<(tert-butyldimethylsilyl)oxy>benzene

: 489422-91-5
tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Guidance literature:: 4-Bromo-2-methoxy-1-<(tert-butyldimethylsilyl)oxy>benzene; With tert.-butyl lithium; In tetrahydrofuran;

With zinc(II) chloride; In tetrahydrofuran;

2,3,5-tribromobenzofuran; With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0040-4039(02)02287-6

Reference yield:

: 23145-07-5
5-bromobenzofuran

: 489422-91-5
tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 23 percent / Br₂ / CH₂Cl₂ / 5 h / Heating

2.1: t-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C

2.2: ZnCl₂ / tetrahydrofuran; pentane / 0.17 h / -78 °C

2.3: 80 percent / [PdCl₂(PPh₃)2] / tetrahydrofuran; pentane / 6 h / 20 °C

With bromine; tert.-butyl lithium; In tetrahydrofuran; dichloromethane; pentane; 2.3: Negishi cross-coupling;

Reference yield:

: 99660-97-6
dibromo-3,5 benzofuranne

: 489422-91-5
tert-butyl[4-(3,5-dibromobenzo[b]furan-2-yl)-2-methoxyphenoxy]dimethylsilane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 95 percent / Br₂ / CH₂Cl₂ / 16 h / Heating

2.1: t-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C

2.2: ZnCl₂ / tetrahydrofuran; pentane / 0.17 h / -78 °C

2.3: 80 percent / [PdCl₂(PPh₃)2] / tetrahydrofuran; pentane / 6 h / 20 °C

With bromine; tert.-butyl lithium; In tetrahydrofuran; dichloromethane; pentane; 2.3: Negishi cross-coupling;