Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Base Information

Chemical Name:Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester
CAS No.:75933-84-5
Molecular Formula:C₄₂H₄₁ClN₃O₁₁P
Molecular Weight:830.228
Hs Code.:

Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Synonyms:Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Suppliers and Price of Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

There total 6 articles about Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

: 75933-84-5
Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Guidance literature:: With N₁,N₁,N₃,N₃-tetramethylguanidium salt of pyridine-2-carboxaldoxime; In 1,4-dioxane; water; at 20 ℃; for 16h; Yield given;
DOI:10.1021/jo00157a001

Reference yield:

: 75933-79-8
5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-uridine-3'-(4-chlorophenyl 5-chloro-8-quinolyl-phosphate)

: 75933-84-5
C₄₁H₄₁ClN₂O₁₂P^(1-)

Guidance literature:: With N₁,N₁,N₃,N₃-tetrametylquanidium salt of 2-pyridinecarboxaldehyde oxim; In 1,4-dioxane; water; at 22 ℃; for 16h;
DOI:10.1021/jo00316a020

Reference yield:

: 51296-18-5
5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-uridine

: 75933-84-5
Phosphoric acid 1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tetrahydro-pyran-2-yloxy)-ethyl ester 5-chloro-quinolin-8-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / 8-quinolinesulfonyltetrazolide / pyridine / 2 h / Ambient temperature

2: N¹,N¹,N³,N³-tetramethylguanidium salt of syn-pyridine-2-carboaldoxime / dioxane; H₂O / 16 h / 20 °C

With N₁,N₁,N₃,N₃-tetramethylguanidium salt of pyridine-2-carboxaldoxime; 8-quinolinesulphonyl tetrazolide; In 1,4-dioxane; pyridine; water;
DOI:10.1021/jo00157a001