<3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone

Base Information

• Chemical Name: <3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone
• CAS No.: 122539-59-7
• Molecular Formula: C₂₇H₂₇NO₅
• Molecular Weight: 445.515

Synonyms:<3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone

Chemical Property of <3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone

Chemical Property:

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Technology Process of <3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone

There total 1 articles about <3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-Benzyloxyphenol (103-16-2) + <3(2R),4R,5S>-3-(2-hydroxy-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone (96930-29-9) → <3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone (122539-59-7)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1021/jo00281a042

Reference yield: 68.0%

<3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone (122539-59-7) → <3(2R),4R,5S>-3-(2-((4-hydroxyphenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone

Guidance literature:

With trimethylsilyl iodide; In dichloromethane; for 0.75h;

DOI:10.1021/jo00281a042

Reference yield:

<3(2R),4R,5S>-3-(2-((4-(benzyloxy)phenyl)oxy)-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone (122539-59-7) → (S)-2-(4-Benzyloxy-phenoxy)-butyramide

Guidance literature:

With dimethylaluminium amide; In hexane; dichloromethane; at 25 ℃; for 7h;

DOI:10.1021/jo00281a042

upstream raw materials:

4-Benzyloxyphenol

<3(2R),4R,5S>-3-(2-hydroxy-1-oxobutyl)-4-methyl-5-phenyl-2-oxazolidinone

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