3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate

Base Information

Chemical Name:3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate
CAS No.:2189-52-8
Molecular Formula:C26H29NO5
Molecular Weight:435.5122
Hs Code.:

Synonyms:3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate;3-alpha-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yloxy)nortropane hydrogen maleate;1-alpha-H,5-alpha-H-Nortropane, 3-alpha-((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-, maleate (1:1);LS-97491;2189-52-8

Suppliers and Price of 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate

Chemical Property:

Vapor Pressure:2.27E-08mmHg at 25°C
Boiling Point:452.3°Cat760mmHg
Flash Point:192.8°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:435.20457303
Heavy Atom Count:32
Complexity:521

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2CC(CC1N2)OC3C4=CC=CC=C4CCC5=CC=CC=C35.C(=CC(=O)O)C(=O)O
Isomeric SMILES:C1C[C@H]2CC(C[C@@H]1N2)OC3C4=CC=CC=C4CCC5=CC=CC=C35.C(=C\C(=O)O)\C(=O)O

Technology Process of 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate

There total 4 articles about 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)nortropane maleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 47337-71-3
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8-azabicyclo[3.2.1]octane

: 110-16-7,26099-09-2
maleic acid

: 2189-52-8
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8-azabicyclo[3.2.1]octane maleate

Guidance literature:: In ethyl acetate;
DOI:10.1016/j.bmcl.2011.12.008

Reference yield:

: 604-51-3
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8-methyl-8-azabicyclo[3.2.1]octane

: 2189-52-8
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8-azabicyclo[3.2.1]octane maleate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium permanganate; potassium hydroxide / pyridine; water / 5 h / 20 °C / Cooling with ice

2: ethyl acetate

With potassium permanganate; potassium hydroxide; In pyridine; water; ethyl acetate;
DOI:10.1016/j.bmcl.2011.12.008

Reference yield:

: 1210-33-9
5-chlorodibenzosuberane

: 2189-52-8
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8-azabicyclo[3.2.1]octane maleate

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 20 °C

2: potassium permanganate; potassium hydroxide / pyridine; water / 5 h / 20 °C / Cooling with ice

3: ethyl acetate

With potassium permanganate; potassium hydroxide; In pyridine; water; ethyl acetate; toluene;
DOI:10.1016/j.bmcl.2011.12.008