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Maleic Acid

Base Information Edit
  • Chemical Name:Maleic Acid
  • CAS No.:110-16-7
  • Deprecated CAS:1975169-66-4
  • Molecular Formula:C4H4O4
  • Molecular Weight:116.073
  • Hs Code.:29173990
  • European Community (EC) Number:203-742-5,607-861-7
  • ICSC Number:1186
  • NSC Number:25940
  • UN Number:2215,3261
  • UNII:91XW058U2C
  • DSSTox Substance ID:DTXSID8021517
  • Nikkaji Number:J2.446E
  • Wikipedia:Maleic_acid
  • Wikidata:Q42038
  • NCI Thesaurus Code:C25951
  • RXCUI:1426330
  • Pharos Ligand ID:G85TY71W8BTL
  • Metabolomics Workbench ID:37118
  • ChEMBL ID:CHEMBL539648
  • Mol file:110-16-7.mol
Maleic Acid

Synonyms:hydrogen maleate;maleate;maleic acid;maleic acid, ammonium salt;maleic acid, calcium salt;maleic acid, dipotassium salt;maleic acid, disodium salt;maleic acid, iron salt;maleic acid, monoammonium salt;maleic acid, monocopper (2+) salt;maleic acid, monosodium salt;maleic acid, neodymium salt;maleic acid, potassium salt;maleic acid, sodium salt;sodium maleate

Suppliers and Price of Maleic Acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Maleic acid 99+%
  • 250g
  • $ 170.00
  • TRC
  • Maleic acid
  • 250g
  • $ 150.00
  • TCI Chemical
  • Maleic Acid >99.0%(T)
  • 500g
  • $ 25.00
  • TCI Chemical
  • Maleic Acid >99.0%(T)
  • 25g
  • $ 19.00
  • SynQuest Laboratories
  • Maleic acid
  • 100 g
  • $ 49.00
  • SynQuest Laboratories
  • Maleic acid
  • 25 g
  • $ 32.00
  • Sigma-Aldrich
  • Maleic acid
  • 50 kg
  • $ 1933.25
  • Sigma-Aldrich
  • Maleic acid ≥99.0% (HPLC)
  • 25kg
  • $ 1220.00
  • Sigma-Aldrich
  • Maleic acid United States Pharmacopeia (USP) Reference Standard
  • 300mg
  • $ 1160.00
  • Sigma-Aldrich
  • Maleic acid
  • 8003809050
  • $ 729.00
Total 234 raw suppliers
Chemical Property of Maleic Acid Edit
Chemical Property:
  • Appearance/Colour:White solid 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:137-140 °C(lit.) 
  • Refractive Index:1.526 
  • Boiling Point:355.5 °C at 760 mmHg 
  • PKA:1.83(at 25℃) 
  • Flash Point:183 °C 
  • PSA:74.60000 
  • Density:1.499 g/cm3 
  • LogP:-0.28820 
  • Storage Temp.:Store at RT. 
  • Solubility.:478.8g/l 
  • Water Solubility.:790 g/L (25 ºC) 
  • XLogP3:-0.3
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:2
  • Exact Mass:116.01095860
  • Heavy Atom Count:8
  • Complexity:119
  • Transport DOT Label:Corrosive

99% *data from raw suppliers

Maleic acid 99+% *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xn 
  • Statements: 22-36/37/38-43 
  • Safety Statements: 26-28-37-28A-46-24 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

  • Chemical Classes:UVCB,Other Classes -> Organic Acids
  • Canonical SMILES:C(=CC(=O)O)C(=O)O
  • Isomeric SMILES:C(=C\C(=O)O)\C(=O)O
  • Recent ClinicalTrials:Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.
  • Inhalation Risk:Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.
  • Effects of Short Term Exposure:The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract.
  • Effects of Long Term Exposure:Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization.
  • Description Maleic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. Its chemical formula is HO2CCHCHCO2H. Maleic acid is the cis-isomer of butenedioic acid, where as fumaric acid is the trans-isomer. It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, maleic acid has few applications.
  • Physical properties Maleic acid is a less stable molecule than fumaric acid. The difference in heat of combustion is 22.7 kJ·mol?1. The heat of combustion is -1355 kJ / mole. Maleic acid is more soluble in water than fumaric acid. The melting point of maleic acid (135 °C) is also much lower than that of fumaric acid (287 °C). Both properties of maleic acid can be explained on account of the intramolecular hydrogen bonding that takes place in maleic acid at the expense of intermolecular interactions, and that are not possible in fumaric acid for geometric reasons.
  • Uses Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.
Technology Process of Maleic Acid

There total 427 articles about Maleic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Refernces Edit
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