Technology Process of N,O-dibenzoyl-4-nitrotryptophanol
There total 13 articles about N,O-dibenzoyl-4-nitrotryptophanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 9 steps
1: thionyl chloride / 1 h., room temp. then 3 h., 60 deg C
2: 88.7 percent / HCl / ethanol / 48 h / Heating
3: 90 percent / NaHCO3 / dioxane; H2O / 40 h / 40 - 45 °C
4: 98 percent / LiBH4 / tetrahydrofuran / 3 h / Ambient temperature
5: pyridine / 18 h / Ambient temperature
6: 2N KOH / methanol; H2O / 144 h / Ambient temperature
7: 85 percent / pyridine / 15 h / Ambient temperature
8: 100 percent / trifluoroacetic acid / CH2Cl2
9: 77 percent / pyridine / 15 h / Ambient temperature
With
hydrogenchloride; potassium hydroxide; lithium borohydride; thionyl chloride; sodium hydrogencarbonate; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; pyridine; methanol; ethanol; dichloromethane; water;
DOI:10.1016/S0040-4020(01)96073-9
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 85 percent / pyridine / 15 h / Ambient temperature
2: 100 percent / trifluoroacetic acid / CH2Cl2
3: 77 percent / pyridine / 15 h / Ambient temperature
With
trifluoroacetic acid;
In
pyridine; dichloromethane;
DOI:10.1016/S0040-4020(01)96073-9
