cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

Base Information

Chemical Name:cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one
CAS No.:1202007-18-8
Molecular Formula:C₂₄H₂₇ClN₂O₂
Molecular Weight:410.944
Hs Code.:

Synonyms:cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

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Chemical Property of cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

Chemical Property:

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Technology Process of cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

There total 5 articles about cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1202007-19-9
cis-1-(4-{[1-(benzyloxy)-7-chloroisoquinolin-6-yl]oxy}-phenylcyclohexyl)-propanamine

: 1202007-18-8
cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

Guidance literature:: With hydrogenchloride; In water; isopropyl alcohol;

Reference yield:

: 923022-53-1
7-chloro-6-fluoro-2H-isoquinolin-1-one

: 1202007-18-8
cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: silver carbonate / tetrahydrofuran / 20 - 70 °C

2.1: sodium hydride / ISOPROPYLAMIDE; mineral oil / 0.17 h / 20 °C

2.2: 72 h

3.1: hydrogenchloride / water; isopropyl alcohol

With hydrogenchloride; sodium hydride; silver carbonate; In tetrahydrofuran; ISOPROPYLAMIDE; water; isopropyl alcohol; mineral oil;

Reference yield:

: 923022-55-3
1-benzyloxy-7-chloro-6-fluoro-isoquinoline

: 1202007-18-8
cis-6-{[4-(1-aminopropyl)-4-phenylcyclohexyl]oxy}-7-chloro-2H-isoquinolin-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / ISOPROPYLAMIDE; mineral oil / 0.17 h / 20 °C

1.2: 72 h

2.1: hydrogenchloride / water; isopropyl alcohol

With hydrogenchloride; sodium hydride; In ISOPROPYLAMIDE; water; isopropyl alcohol; mineral oil;