(18F)fluoroethyltyrosine

Base Information

Chemical Name:(18F)fluoroethyltyrosine
CAS No.:178433-03-9
Molecular Formula:C₁₁H₁₄FNO₃
Molecular Weight:226.237
Hs Code.:
UNII:1326R5J1IA
DSSTox Substance ID:DTXSID601045942
Wikipedia:Fluoroethyl-L-tyrosine_(18F)
Wikidata:Q22908451
NCI Thesaurus Code:C60818
Metabolomics Workbench ID:155470
ChEMBL ID:CHEMBL477278

Synonyms:((18)F)FET;(18F)fluoroethyltyrosine;18F-fluoroethyl-L-tyrosine

Suppliers and Price of (18F)fluoroethyltyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (18F)fluoroethyltyrosine

Chemical Property:

XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:226.098306
Heavy Atom Count:16
Complexity:217

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)N)OCCF
Isomeric SMILES:C1=CC(=CC=C1C[C@@H](C(=O)O)N)OCC[18F]
Recent ClinicalTrials:Registering Genomics and Imaging of Tumors (ReGIT)
Recent EU Clinical Trials:A prospective, multicentre trial on the value of

Technology Process of (18F)fluoroethyltyrosine

There total 10 articles about (18F)fluoroethyltyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: O-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-N-(triphenylmethyl)-L-tyrosine 1,1-dimethylethyl ester

: 178433-03-9
O-(2-[¹⁸F]-fluoroethyl)-L-tyrosine

Guidance literature:: O-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-N-(triphenylmethyl)-L-tyrosine 1,1-dimethylethyl ester; With [¹⁸F]triflyl fluoride; potassium hydrogencarbonate; [2.2.2]cryptande; In acetonitrile; at 100 ℃; for 0.166667h;

With hydrogenchloride; In water; acetonitrile; at 100 ℃; for 0.0833333h;
DOI:10.1039/c8cc03206h

Reference yield:

: 855698-96-3
t-Boc-(O-[18F]fluoroethyl)-L-Tyr-OBzl

: 178433-03-9
O-(2-[¹⁸F]-fluoroethyl)-L-tyrosine

Guidance literature:: t-Boc-(O-[18F]fluoroethyl)-L-Tyr-OBzl; With hydrogenchloride; ethanol; at 100 ℃; for 0.166667h;

With sodium hydroxide; In ethanol; water;