C₅₂H₅₈N₄

Base Information

• Chemical Name: C₅₂H₅₈N₄
• CAS No.: 1453279-69-0
• Molecular Formula: C₅₂H₅₈N₄
• Molecular Weight: 739.059
• Mol file: 1453279-69-0.mol

Synonyms:C₅₂H₅₈N₄

Chemical Property of C₅₂H₅₈N₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₅₂H₅₈N₄

There total 4 articles about C₅₂H₅₈N₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-Ethynylpyridine (2510-23-8) + 3,3'-((1E,1'E)-(2,5-diiodo-1,4-phenylene)bis(ethene-2,1-diyl))bis(N,N-dibutylaniline) (1453279-76-9) → C52H58N4 (1453279-69-0)

Guidance literature:

With copper(l) iodide; bis(triphenylphosphine)palladium(II) chloride; diisopropylamine; In tetrahydrofuran; at 20 ℃; for 72h;

DOI:10.1002/chem.201300211

Reference yield:

m-Bromoaniline (591-19-5) → C52H58N4 (1453279-69-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium carbonate / tetrahydrofuran / 72 h / 50 °C / Inert atmosphere

2.1: n-butyllithium / hexane; tetrahydrofuran / 2 h / -78 °C

2.2: 0.5 h

3.1: potassium tert-butylate / tetrahydrofuran / 0 °C / Inert atmosphere

4.1: bis(triphenylphosphine)palladium(II) chloride; copper(l) iodide; diisopropylamine / tetrahydrofuran / 72 h / 20 °C

With copper(l) iodide; n-butyllithium; bis(triphenylphosphine)palladium(II) chloride; potassium tert-butylate; potassium carbonate; diisopropylamine; In tetrahydrofuran; hexane; 3.1: |Horner-Wadsworth-Emmons Olefination / 4.1: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201300211

Reference yield:

3-N,N-dibutylaminobenzaldehyde → C52H58N4 (1453279-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 0 °C / Inert atmosphere

2: bis(triphenylphosphine)palladium(II) chloride; copper(l) iodide; diisopropylamine / tetrahydrofuran / 72 h / 20 °C

With copper(l) iodide; bis(triphenylphosphine)palladium(II) chloride; potassium tert-butylate; diisopropylamine; In tetrahydrofuran; 1: |Horner-Wadsworth-Emmons Olefination / 2: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201300211

upstream raw materials:

m-Bromoaniline

3-Ethynylpyridine

3,3'-((1E,1'E)-(2,5-diiodo-1,4-phenylene)bis(ethene-2,1-diyl))bis(N,N-dibutylaniline)

3-bromo-N,N-dibutylaniline