Technology Process of 2-(1-allyl-1H-indol-3-yl)-N-benzylacetamide
There total 3 articles about 2-(1-allyl-1H-indol-3-yl)-N-benzylacetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutylammomium bromide; potassium hydroxide;
In
acetonitrile;
for 8h;
Reflux;
DOI:10.1021/ja305100g
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diethyl ether
2: sodium acetate; hydrazine hydrate / ethyl methyl ether
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
4: tetrabutylammomium bromide; potassium hydroxide / acetonitrile / 8 h / Reflux
With
tetrabutylammomium bromide; sodium acetate; hydrazine hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium hydroxide;
In
diethyl ether; ethyl methyl ether; dichloromethane; acetonitrile;
DOI:10.1021/ja305100g
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
2: tetrabutylammomium bromide; potassium hydroxide / acetonitrile / 8 h / Reflux
With
tetrabutylammomium bromide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium hydroxide;
In
dichloromethane; acetonitrile;
DOI:10.1021/ja305100g
