3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline

Base Information

Chemical Name:3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline
CAS No.:1355253-88-1
Molecular Formula:C₃₂H₂₆ClN₃
Molecular Weight:488.032
Hs Code.:

Synonyms:3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline

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Technology Process of 3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline

There total 2 articles about 3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1-hydrazino-3-(4-chlororphenyl)isoquinoline

: 52182-27-1
C₁₇H₁₆O

: 1355253-88-1
3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline

Guidance literature:: With Ironoxide nanoparticles; In ethanol; for 0.5h; Reflux;
DOI:10.1007/s11164-011-0372-1

Reference yield:

: 104-87-0
4-methyl-benzaldehyde

: 585-74-0
3-Methylacetophenone

: 1355253-88-1
3-(4-chlorophenyl)-1-{5-(4-methylphenyl)-3-(3-methyl phenyl)-4,5-dihydro-1H-pyrazol-1-yl}isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / 20 °C

2: Ironoxide nanoparticles / ethanol / 0.5 h / Reflux

With sodium hydroxide; In ethanol; 1: Aldol condensation;
DOI:10.1007/s11164-011-0372-1