2,2,2-trichloro-1-styrylethyl acetate

Base Information

• Chemical Name: 2,2,2-trichloro-1-styrylethyl acetate
• CAS No.: 118171-44-1
• Molecular Formula: C₁₂H₁₁Cl₃O₂
• Molecular Weight: 293.577
• Mol file: 118171-44-1.mol

Synonyms:2,2,2-trichloro-1-styrylethyl acetate

Chemical Property of 2,2,2-trichloro-1-styrylethyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trichloro-1-styrylethyl acetate

There total 7 articles about 2,2,2-trichloro-1-styrylethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

acetic anhydride (108-24-7) + (E)-1,1,1-trichloro-4-phenylbut-3-en-2-ol (96349-58-5) → 2,2,2-trichloro-1-styrylethyl acetate (118171-44-1)

Guidance literature:

With dmap; In pyridine; at 20 ℃; for 2h;

DOI:10.1021/jo010068c

Reference yield: 62.0%

chloroform (67-66-3,8013-54-5) + 1,1-diacetoxy-3-phenylprop-2-ene (37973-54-9,64847-78-5) → 2,2,2-trichloro-1-styrylethyl acetate (118171-44-1)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; for 1h; Ambient temperature;

DOI:10.1016/S0040-4039(00)87684-4

Reference yield:

(E)-3-phenylpropenal (14371-10-9) → 2,2,2-trichloro-1-styrylethyl acetate (118171-44-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / CCl₃CO₂H / dimethylformamide / 20 °C

2: 82 percent / DMAP / pyridine / 2 h / 20 °C

With dmap; trichloroacetic acid; In pyridine; N,N-dimethyl-formamide;

DOI:10.1021/jo010068c

upstream raw materials:

1,1,1-trichloro-4-phenyl-but-3-en-2-ol

acetyl chloride

chloroform

1,1-diacetoxy-3-phenylprop-2-ene

Downstream raw materials:

1-phenyl-4,4-dichloro-1,3-butadiene

(1Z,3E)-1-chloro-4-phenylbuta-1,3-dienyl acetate

1-[(1E)-4,4-dichloro-1,3-butadienyl]benzene