dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

Base Information

Chemical Name:dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate
CAS No.:1012919-06-0
Molecular Formula:C₂₄H₂₆ClFO₅
Molecular Weight:448.919
Hs Code.:

Synonyms:dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

Suppliers and Price of dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

There total 3 articles about dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1117-19-7
dipropyl malonate

: 28081-11-0
3-(2-chlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one

: 1012919-06-0
dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

Guidance literature:: With (1R,2R)-1,2-diphenylethane-1,2-bis(2,5-dimethylphenyl)sulfonamide; strontium bis; In toluene; at 25 ℃; for 7h; optical yield given as %ee; enantioselective reaction;
DOI:10.1246/cl.2009.296

Reference yield: 80.0%

: 1012919-06-0
dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

Guidance literature:

Reference yield:

: 1117-19-7
dipropyl malonate

: 452332-71-7
(2E)-3-(2-chlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one

: 1012919-06-0
dipropyl 2-(1-(2-chlorophenyl)-3-(4-fluorophenyl)-3-oxopropyl)malonate

: C₂₄H₂₆ClFO₅

Guidance literature:: With 4 A molecular sieve; Sr(O-i-Pr)2; (1R,2R)-1,2-diphenylethane-1,2-bis(2,5-Me₂C₆H₃)sulfonamide; In chloroform-d1; at 25 ℃; for 7h; Title compound not separated from byproducts.;
DOI:10.1021/ja710332h