1-Benzyl-4-(4-methanesulfonylphenyl)piperazine

Base Information

Chemical Name:1-Benzyl-4-(4-methanesulfonylphenyl)piperazine
CAS No.:166438-71-7
Molecular Formula:C₁₈H₂₂N₂O₂S
Molecular Weight:330.451
Hs Code.:
DSSTox Substance ID:DTXSID601206744

Synonyms:166438-71-7;1-benzyl-4-(4-methanesulfonylphenyl)piperazine;SCHEMBL4539301;DTXSID601206744;AKOS040882543;FT-0740786;1-[4-(Methylsulfonyl)phenyl]-4-(phenylmethyl)piperazine;F6807-7037

Suppliers and Price of 1-Benzyl-4-(4-methanesulfonylphenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Benzyl-4-(4-methanesulfonylphenyl)piperazine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:330.14019912
Heavy Atom Count:23
Complexity:452

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC=C(C=C1)N2CCN(CC2)CC3=CC=CC=C3

Technology Process of 1-Benzyl-4-(4-methanesulfonylphenyl)piperazine

There total 1 articles about 1-Benzyl-4-(4-methanesulfonylphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2759-28-6
1-phenylmethylpiperazine

: 3466-32-8
4-bromoohenyl methyl sulfone

: 166438-71-7
1-benzyl-4-[4-(methylsulfonyl)phenyl]piperazine

Guidance literature:: With caesium carbonate; palladium diacetate; XPhos; In ISOPROPYLAMIDE; at 150 ℃; for 1h; Inert atmosphere; Microwave irradiation;

Reference yield:

: 166438-71-7
1-benzyl-4-[4-(methylsulfonyl)phenyl]piperazine

: 187669-60-9
1-(4-methanesulfonyl-phenyl)-piperazine

Guidance literature:: With hydrogen; palladium hydroxide, 20 wt% on carbon; In methanol; for 3h; under 760.051 Torr;

Reference yield:

: 166438-71-7
1-benzyl-4-[4-(methylsulfonyl)phenyl]piperazine

: 1396675-72-1
C₂HF₃O₂*C₂₃H₂₂ClN₅O₂S

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium hydroxide, 20 wt% on carbon / methanol / 3 h / 760.05 Torr

2: N-ethyl-N,N-diisopropylamine / ISOPROPYLAMIDE / 16 h / 110 °C / Inert atmosphere

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium hydroxide, 20 wt% on carbon; In methanol; ISOPROPYLAMIDE;