Diethylhomospermine

Base Information

Chemical Name:Diethylhomospermine
CAS No.:119422-08-1
Molecular Formula:C₁₆H₃₈N₄
Molecular Weight:286.505
Hs Code.:
NSC Number:741423
UNII:8G6X94GNHO
DSSTox Substance ID:DTXSID20152459
Nikkaji Number:J415.690K
Wikidata:Q27270391
NCI Thesaurus Code:C2412
Metabolomics Workbench ID:153890
ChEMBL ID:CHEMBL77101
Mol file:119422-08-1.mol

Synonyms:1,14-bis(ethylamino)-5,10-diazatetradecane;BE-4-4-4;BEHSpm;DEHSPM;N(1),N(14)-bis(ethyl)homospermine;N(1),N(14)-diethylhomospermine

Suppliers and Price of Diethylhomospermine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N1,N14-BIS(ETHYL)HOMOSPERMINE 95.00%
5MG
$ 495.26

Total 6 raw suppliers

Chemical Property of Diethylhomospermine

Chemical Property:

Vapor Pressure:3.73E-06mmHg at 25°C
Refractive Index:1.4850 (estimate)
Boiling Point:385.7°C at 760 mmHg
Flash Point:187.5°C
PSA：48.12000
Density:0.873g/cm³
LogP:3.28880
XLogP3:1.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:17
Exact Mass:286.30964723
Heavy Atom Count:20
Complexity:147

Purity/Quality:

98%min ^*data from raw suppliers

N1,N14-BIS(ETHYL)HOMOSPERMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCNCCCCNCCCCNCCCCNCC
Recent ClinicalTrials:Diethylhomospermine (DEHSPM) for Refractory AIDS-Related Diarrhea

Technology Process of Diethylhomospermine

There total 2 articles about Diethylhomospermine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 161452-30-8
N¹,N⁵,N¹⁰,N¹⁴-tetrakis(mesitylenesulfonyl)-N¹,N¹⁴-diethylhomospermine

: 119422-08-1
1,14-bis(ethylamino)-5,10-diazatetradecane

Guidance literature:: With hydrogen bromide; acetic acid; phenol; In dichloromethane; at 0 - 20 ℃; for 24h;
DOI:10.1021/jm00047a004

Reference yield:

: 161452-15-9
N-(4-bromobutyl)-N-ethylmesitylenesulfonamide

: 119422-08-1
1,14-bis(ethylamino)-5,10-diazatetradecane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, a) RT, 30 min, b) 72 deg C, 16 h

2: 30percent HBr, HOAc, phenol / CH₂Cl₂ / 24 h / 0 - 20 °C

With hydrogen bromide; sodium hydride; acetic acid; phenol; In dichloromethane;
DOI:10.1021/jm00047a004