2-(4-methylphenyl)-5-propylthiophene

Base Information

• Chemical Name: 2-(4-methylphenyl)-5-propylthiophene
• CAS No.: 1127217-50-8
• Molecular Formula: C₁₄H₁₆S
• Molecular Weight: 216.347
• Mol file: 1127217-50-8.mol

Synonyms:2-(4-methylphenyl)-5-propylthiophene

Chemical Property of 2-(4-methylphenyl)-5-propylthiophene

Chemical Property:

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Technology Process of 2-(4-methylphenyl)-5-propylthiophene

There total 1 articles about 2-(4-methylphenyl)-5-propylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-propylthiophene (1551-27-5) + para-bromotoluene (106-38-7) → 2-(4-methylphenyl)-5-propylthiophene (1127217-50-8)

Guidance literature:

With 2-bis[2,6-bis(trifluoromethyl)-4-pyridyl]phosphino-2′,6′-dimethoxybiphenyl; palladium diacetate; potassium carbonate; Trimethylacetic acid; In N,N-dimethyl acetamide; at 100 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c5dt01991e

upstream raw materials:

2-propylthiophene

para-bromotoluene

Refernces

• 1、 Liegault, Benoit,Lapointe, David,Caron, Laurence,Vlassova, Anna,Fagnou, Keith. "Establishment of broadly applicable reaction conditions for the palladium-catalyzed direct arylation of heteroatom-containing aromatic compounds". scheme or table. p. 1826 - 1834. Retrieved 2009/07/01.