1551-27-5

Usage

Chemical Properties

Brown liquid

InChI:InChI=1/C7H10S/c1-6(2)7-4-3-5-8-7/h3-6H,1-2H3

Upstream product

• 96-43-5 2-thienyl chloride 
• 13679-75-9 1-thiophen-2-yl-propan-1-one 
• 15022-18-1 1-(thiophen-2-yl)propan-2-one 
• 111-65-9 octane 
• 20849-87-0 2-allylthiophene 
• 109-64-8 1,3-dibromo-propane 
• 106-94-5 propyl bromide 
• 142-82-5 n-heptane 
• 188290-36-0 thiophene 
• 3437-95-4 2-Iodothiophene 

Downstream Products

• 35250-76-1 5-n-propylthiophene-2-carbaldehyde 
• 1127217-50-8 2-(4-methylphenyl)-5-propylthiophene 
• 1191913-98-0 3-methyl-3-((5-propylthiophen-2-yl)methyl)-1-tosylindoline 
• 1191914-00-7 1-(4-methoxybenzyl)-3-methyl-3-((5-propylthiophen-2-yl)methyl)indolin-2-one 
• 1353658-85-1 2-(3,5-dimethylphenyl)-5-propylthiophene 
• 1094440-92-2 1-(5-(3,5-dimethylphenyl)thiophen-2-yl)ethanone 
• 893735-21-2 1-{5-[4-(trifluoromethyl)phenyl]thiophen-2-yl}ethanone 
• 1127217-52-0 2-propyl-5-(4-(trifluoromethyl)phenyl)thiophene 
• 1375353-48-2 2-(2-(2-(4-(5-propylthiophen-2-yl)phenoxy)ethoxy)ethoxy)ethanol 
• 1375353-54-0 sodium 2-(2-(2-(2-(4-(5-propylthiophen-2-yl)phenoxy)ethoxy)ethoxy)ethoxy)acetate 
• 1429918-63-7 N-(diphenylmethylene)-5,5'-dipropyl-2,2'-bithiophen-3-amine 
• 13679-75-9 1-thiophen-2-yl-propan-1-one 
• 100713-10-8 2-phenyl-5-propylthiophene 
• 1259389-29-1 5-(4-(trifluoromethyl)phenyl)-2-isobutylthiazole 

Relevant academic research and scientific papers

CATALYST COMPOSITION INCLUDING NOVEL TRANSITION METAL COMPOUND

The present invention relates to a catalyst composition including a transition metal compound represented by the following Formula 1; and one or more of a compound represented by the following Formula 2, a compound represented by the following Formula 3 and a compound represented by the following Formula 4. The catalyst composition according to the present invention has excellent copolymerization properties, and can be usefully used as a catalyst for a polymerization reaction for preparing an olefin-based polymer having a high molecular weight.

DIARYL[A, G]QUINOLIZIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF

The present invention relates to a diarylo[a,g]quinolizidine compound of formula (I), enantiomer, diastereoisomer, racemate, mixture, pharmaceutically acceptable salt, crystalline hydrate or solvate thereof; the preparation method thereof, and uses thereof in preparing an experimental model drugs related to dopamine receptors and 5-HT receptors or a medicament for treating or preventing a disease related to dopamine receptors and 5-HT receptors.

DIARYL[A, G]QUINOLIZIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF

The present invention relates to a diarylo[a,g]quinolizidine compound of formula (I), enantiomer, diastereoisomer, racemate, mixture, pharmaceutically acceptable salt, crystalline hydrate or solvate thereof; the preparation method thereof, and uses thereof in preparing an experimental model drugs related to dopamine receptors and 5-HT receptors or a medicament for treating or preventing a disease related to dopamine receptors and 5-HT receptors.

Synthesis and mesophase behavior of phenylthiophene based amphiphilic molecules

Novel amphiphilic molecules consisting of a rigid 2-phenylthiophene core, with a polar flexible tri(oxylethylene) moiety attached to the phenyl ring and one or two alkyl chains attached to the thiophene ring at the other side have been synthesized by using Ni(II) and Pd(0) catalyzed coupling reaction as key steps. The tri(oxylethylene) moieties were terminated with hydroxyl group, sodium carboxylate group and lithium carboxylate group respectively. The thermotropic and solvent induced liquid crystalline behavior of these substances was investigated by polarized optical microscopy, differential scanning calorimetry and X-ray diffraction. Thereby the influence of the terminal groups attached to the tri(oxylethylene) moities as well as the influence of the length and the number of the alkyl chains on the mesophase behavior were investigated. The single alkyl chain Na-carboxylate termianted derivatives show smectic A phases, double alkyl chain Na-carboxylate terminated derivatives show a thermo tropic hexagonal columnar mesophase, while columnar mesophases are found in both single and double alkyl chain Li-carbonate terminated derivatives. The model for molecular organization in the hexagonal columnar mesophase is established.

At the frontier between heterogeneous and homogeneous catalysis: Hydrogenation of olefins and alkynes with soluble iron nanoparticles

The use of non-supported Fe nanoparticles in the hydrogenation of unsaturated C-C bonds is a green catalytic concept at the frontier between homogeneous and heterogeneous catalysis. Iron nanoparticles can be obtained by reducing Fe salts with strong reductants in various solvents. FeCl3 reduced by 3 equivalents of EtMgCl forms an active catalyst for the hydrogenation of a range of olefins and alkynes. Olefin hydrogenation is relatively fast at 5 bar using 5 mol% of catalyst. The catalyst is also active for terminal olefins and 1,1′ and 1,2-cis disubstituted olefins while trans-olefins react much slower. 1-Octyne is hydrogenated to mixtures of 1-octene and octane. Kinetic studies led us to propose a mechanism for this latter transformation where octane is obtained by two different pathways. Characterization of the nanoparticles via TEM, magnetic measurements and poisoning experiments were undertaken to understand the true nature of our catalyst.

Organic semiconductors with helical structure based on oligothiophene derivatives exhibiting chiral nematic phase

We have synthesized 2-[5-(4-[(S)-2-methylbutoxy]phenyl)-3-methyl]-2'''- propyl-2:5'-2':5''-2'':5'''-quaterthiophene (10), a liquid crystalline semiconductor that exhibits a chiral nematic phase, and used the time-of-flight technique to determine its carrier mobility behavior. In the chiral nematic phase, the positive carrier mobility was 210-4cm2/Vs at 120C and the negative carrier mobility was 110-4cm2/Vs, both of which we attribute to electronic processes. For the negative carrier, in addition to the fast electronic process, we also observed a slow carrier transport, having mobility on the order of 10-5cm2/Vs, which we attribute to ionic conduction. Chiral dimers containing binaphthyl group exhibited stable glassy cholesteric phase and cholesteric thin films with selective reflection band in visible light area could be fabricated. They emitted circularly polarized light with dichroic parameter of 1.3 when UV light was illuminated.

Synthesis and the effect of alkyl chain length on optoelectronic properties of diarylethene derivatives

Photochromic symmetrical diarylethene derivatives 1a-6a bearing different long alkyl chains at 2-position of thiophene rings have been synthesized and their structures have been determined by single-crystal X-ray diffraction analysis. The effect of alkyl chain length on their optoelectronic properties, such as photochromism in solution as well as in the crystalline phase and electrochemical performance was investigated in detail. These diarylethenes have showed good photochromic behavior both in solution and in the single crystalline phase. Introduction of the long alkyl chains at 2-position of bis(5-formyl-3-thienyl)perfluorocyclopentene increased the absorption coefficients of both open- and closed-ring isomers and induced bathochromic shifts of the maximal wavelength absorption of the closed-ring isomers. The long alkyl chains can also decrease the cyclization/cycloreversion quantum yields and the oxidation potentials. The cyclic voltammetry indicated that the band gap of these diarylethene derivatives was significantly affected by the alkyl chain length.

Antitumor compositions and methods of treatment

This invention provides certain sulfonamide compounds, formulations and method of use of certain sulfonamide compounds in treating susceptible neoplasms.

Enantioselective Synthesis of (S)-2-Methyl-1-alkanols via Bakers'Yeast Mediated Reduction of α-Methyl-2-thiophenepropenals

The bakers'yeast mediated enantioselective reductions of some α-methyl-5-(1-alkyl)-2-thiophenepropenals 3 are described.These furnished (S)-β-methyl-5-(1-alkyl)-2-thiophenepropanols 5 in good to high enantiomeric excesses (76-98percent ee).An alternative approach to (S)-β-methyl-5-(1-alkyl)-2-thiophenepropanols 5d-f (98percent ee) is also described.Raney nickel reduction of their acetates, followed by hydrolysis, provided (S)-2-methyl-1-alkanols 2b-f of unchanged optical purities.

Sulfonylureas: A new class of cancer chemotherapeutic agents

This study summarizes the antitumor properties of a number of sulofenur thiophene analogs against subcutaneously implanted 6C3HED lymphosarcoma with structural modification of the aryl moiety of the sulfonamide portion of the diarylsulfonylureas. The spectrum of activity of N-(p-chlorophenyl)-N'-[(5- methoxy-2-thienyl)sulfonyl]urea in the HXGC3, VRC5, CX-1, and LX-1 cell lines is also presented.