3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole

Base Information

Chemical Name:3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole
CAS No.:1228375-30-1
Molecular Formula:C₁₇H₉Cl₂F₃N₄O₂
Molecular Weight:429.185
Hs Code.:

Synonyms:3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole

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Chemical Property of 3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole

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Technology Process of 3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole

There total 1 articles about 3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 934606-28-7
2-chloro-4-methoxy-N'-hydroxy-benzimidamide

: 353258-35-2
8-chloro-6-(trifluoromethyl)-imidazo[1,2-a]pyridine-2-carboxylic acid

: 1228375-30-1
3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 - 100 ℃; for 13h;

Reference yield: 90.0%

: 1228375-30-1
3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole

: 1228375-09-4
3-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)phenol

Guidance literature:: 3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole; With boron tribromide; In toluene; at 15 - 20 ℃;

With water; In toluene; Cooling with ice;