353258-35-2

Usage

Uses

Used in Pharmaceutical Industry:
8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid is used as a potential antineoplastic agent for the treatment of cancer. Its unique structure and properties have been investigated for their potential in targeting and inhibiting the growth of cancer cells, offering a new avenue for cancer therapy.
Used in Antibacterial Applications:
8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid is used as a potential antibacterial agent against a range of bacterial strains. Its demonstrated activity against various bacteria makes it a promising candidate for the development of new antibiotics, addressing the growing need for effective treatments against drug-resistant infections.
Used in Medical Research:
8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid is used as a subject of research in the medical field to explore its potential applications and mechanisms of action. Further studies are needed to understand its full potential and optimize its use in the development of new therapeutic agents for various diseases.

Upstream product

• 353258-31-8 8-chloro-6-(trifluoromethyl)imidazo[1,2,a]pyridine-2-carboxylic acid ethyl ester 
• 79456-26-1 2-amino-3-chloro-5-(trifluoromethyl)pyridine 

Downstream Products

• 1228376-14-4 8-chloro-2-(3-(2-chloro-4-nitrophenyl)-1,2,4-oxadiazol-5-yl)-6-(trifluoromethyl)-imidazo[1,2-a]pyridine 
• 1228375-18-5 ethyl 3-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)benzoate 
• 1228375-30-1 3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole 
• 1228375-15-2 5-(8-chloro-6-(trifluoromethyl)imidazol[1,2-a]pyridine-2-yl)-3-(2,5-dichloro-4-methoxyphenyl)-1,2,4-oxadiazole 
• 1228375-36-7 3-(4-(allyloxy)-2,5-dichlorophenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole 
• 1228375-37-8 3-(4-(allyloxy)-2-chlorophenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole 
• 1228376-06-4 tert-butyl 3-(3-chloro-4-(5-(8-chloro-6-(trifluoromethyl)-imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)phenyl)propanoate 
• 1228376-36-0 tert-butyl 3-(2,5-dichloro-4-(5-(8-chloro-6-(trifluoromethyl)-imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)phenyl)propanoate 
• 1228376-43-9 8-chloro-2-[3-(2-chloro-5-fluoro-4-methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-6-trifluoromethyl-imidazo[1,2-a]pyridine 
• 1228375-42-5 tert-butyl 3-(5-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-yl)-1,3,4-oxadiazol-2-yl)-2-fluorophenyl)propanoate 
• 1228376-10-0 tert-butyl 3-(5-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)-2-fluorophenyl)propanoate 
• 1254304-22-7 8-chloro-N-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)-imidazo[1,2-a]pyridine-2-carboxamide 
• 1254306-70-1 C₁₇H₁₃Cl₂F₃N₄O₃S 
• 1254306-76-7 C₁₆H₁₀Cl₂F₃N₃O₃S₂ 

Relevant academic research and scientific papers

Nitrogenous heterocyclic compound with nematocidal activity, preparation method and application thereof

The invention relates to a nitrogenous heterocyclic compound with nematocidal activity, a preparation method and application thereof. Specifically, the invention discloses a compound with a formula (I) or an optical isomer, cis-trans isomer or acceptable salt in agricultural pharmacology and a preparation method thereof. The invention further discloses an agricultural composition containing the compound and application thereof. The compound has excellent nematocidal activity.

PRODRUGS FOR THE TREATMENT OF DISEASE

Described herein are prodrugs of heterocyclic compounds, compositions, and methods for their use for the treatment of disease.

HETERCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE

Described herein are heterocyclic compounds, compositions, and methods for their use for treatment of disease.

HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE

Described herein are heterocyclic compounds, compositions, and methods for their use for the treatment of disease.

The discovery of fluazaindolizine: A new product for the control of plant parasitic nematodes

Fluazaindolizine is a new highly effective and selective product for the control of plant parasitic nematodes. Specificity for nematodes coupled with absence of activity against the target sites of commercial nematicides suggests that fluazaindolizine has a novel mode of action. The discovery, structure-activity development and biological properties for this new class of nematicides are presented.

IMIDAZO [1,2A] PYRIDINE DERIVATIVES, THEIR USE AS S1P1 AGONISTS AND METHODS FOR THEIR PRODUCTION

The invention is directed to Compounds of Formula (I) as well as methods of making and using the compounds.

NEMATOCIDAL SULFONAMIDES

Disclosed are compounds of Formula 1 (see "Formula 1"), N-oxides, and salts thereof, wherein Z is O or S; and R1, R2, R3, Q and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or a composition of the invention.