Hypolaetin

Base Information

Chemical Name:Hypolaetin
CAS No.:27696-41-9
Molecular Formula:C15H10 O7
Molecular Weight:302.24
Hs Code.:2914501900
UNII:P9TM8PY56J
ChEMBL ID:CHEMBL1829395
DSSTox Substance ID:DTXSID70415167
Metabolomics Workbench ID:24480
Nikkaji Number:J53.100F
Wikidata:Q15411029
Wikipedia:Hypolaetin
Mol file:27696-41-9.mol

Synonyms:Hypolaetin;8-Hydroxyluteolin;27696-41-9;Isoorientingic;2-(3,4-dihydroxyphenyl)-5,7,8-trihydroxychromen-4-one;P9TM8PY56J;CHEBI:5837;3',4',5,7,8-Pentahydroxyflavone;Flavone, 3',4',5,7,8-pentahydroxy-;UNII-P9TM8PY56J;SCHEMBL7743466;CHEMBL1829395;DTXSID70415167;LMPK12111397;Q15411029;2-(3,4-dihydroxyphenyl)-5,7,8-trihydroxy-4H-chromen-4-one

Suppliers and Price of Hypolaetin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of Hypolaetin

Chemical Property:

Vapor Pressure:1.14E-17mmHg at 25°C
Melting Point:0.300 °C (approx)
Boiling Point:653.3°Cat760mmHg
PKA:6.65±0.40(Predicted)
Flash Point:252.3°C
PSA：131.36000
Density:1.763g/cm³
LogP:1.98800
XLogP3:2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:302.04265265
Heavy Atom Count:22
Complexity:477

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O

Technology Process of Hypolaetin

There total 19 articles about Hypolaetin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89456-17-7
1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-benzyloxy-3-methoxy-phenyl)-propane-1,3-dione

: 27696-41-9
3′,4′,5,7,8-pentahydroxyflavone

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C

2: 80 percent / H₂ / 10percent Pd/C / ethyl acetate; methanol

3: AlBr₃ / acetonitrile / 50 °C

With aluminum tri-bromide; hydrogen; sodium acetate; palladium on activated charcoal; In methanol; acetic acid; ethyl acetate; acetonitrile;
DOI:10.1246/bcsj.56.3773

Reference yield:

: 1486-52-8
3-methoxy-4-benzyloxybenzoyl chloride

: 27696-41-9
3′,4′,5,7,8-pentahydroxyflavone

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 2 h / 120 °C

2: KOH, pyridine / 4 h / 60 °C

3: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C

4: 80 percent / H₂ / 10percent Pd/C / ethyl acetate; methanol

5: AlBr₃ / acetonitrile / 50 °C

With pyridine; potassium hydroxide; aluminum tri-bromide; hydrogen; sodium acetate; palladium on activated charcoal; In methanol; acetic acid; ethyl acetate; acetonitrile;
DOI:10.1246/bcsj.56.3773

Reference yield:

: 21919-66-4
2,30dihydroxy-4,6-dimethoxyacetophenone

: 27696-41-9
3′,4′,5,7,8-pentahydroxyflavone

Guidance literature:: Multi-step reaction with 7 steps

1: K₂CO₃ / dimethylformamide / 3 h / Heating

2: conc.HCl / acetic acid / 1.42 h / Ambient temperature

3: pyridine / 2 h / 120 °C

4: KOH, pyridine / 4 h / 60 °C

5: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C

6: 80 percent / H₂ / 10percent Pd/C / ethyl acetate; methanol

7: AlBr₃ / acetonitrile / 50 °C

With pyridine; hydrogenchloride; potassium hydroxide; aluminum tri-bromide; hydrogen; sodium acetate; potassium carbonate; palladium on activated charcoal; In methanol; acetic acid; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1246/bcsj.56.3773