21919-66-4

Upstream product

• 7508-05-6 1-(2,3,4,6-tetramethoxyphenyl)ethanone 
• 5333-45-9 1,2,3,5-tetramethoxybenzene 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 21919-65-3 2-Hydroxy-4,6-dimethoxy-3-acetoxy-acetophenon 
• 75-36-5 acetyl chloride 
• 89880-47-7 3-ethoxy-2-hydroxy-4,6-dimethoxyacetophenone 
• 7507-98-4 1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone 

Downstream Products

• 89456-26-8 3,4-Bis-benzyloxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 
• 89456-19-9 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(3,4-bis-benzyloxy-phenyl)-propane-1,3-dione 
• 89456-33-7 8-Benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-5,7-dimethoxy-chromen-4-one 
• 89456-24-6 4-Benzyloxy-3-methoxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 
• 89456-25-7 3-Benzyloxy-4-methoxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 
• 89456-17-7 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-benzyloxy-3-methoxy-phenyl)-propane-1,3-dione 
• 89456-18-8 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(3-benzyloxy-4-methoxy-phenyl)-propane-1,3-dione 
• 89456-32-6 8-Benzyloxy-2-(3-benzyloxy-4-methoxy-phenyl)-5,7-dimethoxy-chromen-4-one 
• 89456-31-5 8-Benzyloxy-2-(4-benzyloxy-3-methoxy-phenyl)-5,7-dimethoxy-chromen-4-one 
• 89456-22-4 4-Benzyloxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 
• 89456-27-9 3,4,5-Trimethoxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 
• 89456-20-2 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propane-1,3-dione 
• 89456-15-5 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-benzyloxy-phenyl)-propane-1,3-dione 
• 89456-29-1 8-Benzyloxy-2-(4-benzyloxy-phenyl)-5,7-dimethoxy-chromen-4-one 

Relevant academic research and scientific papers

Regioselective hydroxylation of 2-hydroxychalcones by dimethyldioxirane towards polymethoxylated flavonoids

The flavone nucleus is part of a large number of natural products and medicinal compounds. In this presentation the novel regioselective hydroxylation of hydroxyarenes with DMD is described. The results showed further that flavonoids with 5-hydroxy group were selectively oxyfunctionalized at the para-position C8 carbon atom by DMD. Finally, according to this methodology, the naturally occurring isosinensetin, tangeretin, sinensetin, nobiletin, natsudaidain, gardenin B, 3,3′,4′,5,6,7,8- heptamethoxyflavone, quercetin and its derivatives were synthesized.

Oxidative Rearrangement of Quinochalcones. Part 2. A Facile Synthesis of Linderone

Friedel-Crafts acylation of 1,2,3,5-tetramethoxybenzene in diethyl ether afforded besides the acetophenone (6a), an abnormal product shown to be 3-ethoxy-2-hydroxy-4,6-dimethoxy-acetophenone (6b).Methylpedicinin (1b), prepared from compoumd (6a), was foun