3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone

Base Information

• Chemical Name: 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone
• CAS No.: 945772-22-5
• Molecular Formula: C₁₈H₂₆O₄Si
• Molecular Weight: 334.488
• Mol file: 945772-22-5.mol

Synonyms:3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone

Chemical Property of 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone

There total 1 articles about 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran (945772-24-7) → 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone (945772-22-5)

Guidance literature:

With manganese(IV) oxide; In dichloromethane;

DOI:10.1021/jo701656z

Reference yield: 69.0%

3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone (945772-22-5) + N-(2-iodo-5-methoxyphenyl)acetamide → 1-(2-(tert-butyldimethylsilyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)ethanone (1221257-68-6)

Guidance literature:

With sodium carbonate; lithium chloride; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃;

Reference yield: 69.0%

2-isopropoxy-3-methoxy-6-iodophenol (905751-80-6) + 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone (945772-22-5) → 2-t-butyldimethylsilyl-7-isopropoxy-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan (905752-33-2)

Guidance literature:

With palladium diacetate; sodium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/jm200454y

upstream raw materials:

2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran

Downstream raw materials:

2-t-butyldimethylsilyl-7-isopropoxy-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan

2-t-butyldimethylsilyl-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan

1-(2-(tert-butyldimethylsilyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)ethanone

C₂₅H₃₂O₇Si