2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran

Base Information

• Chemical Name: 2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran
• CAS No.: 945772-24-7
• Molecular Formula: C₁₈H₂₈O₄Si
• Molecular Weight: 336.503
• Mol file: 945772-24-7.mol

Synonyms:2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran

Chemical Property of 2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran

There total 1 articles about 2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(tert-butyldimethylsilyl)acetylene (86318-61-8) + 3,4,5-trimethoxy-benzaldehyde (86-81-7) → 2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran (945772-24-7)

Guidance literature:

(tert-butyldimethylsilyl)acetylene; With n-butyllithium; In tetrahydrofuran; at -78 - -60 ℃; for 1h;

3,4,5-trimethoxy-benzaldehyde; In tetrahydrofuran; at 20 ℃; for 1h; Further stages.;

DOI:10.1021/jo701656z

Reference yield:

2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran (945772-24-7) → 3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone (945772-22-5)

Guidance literature:

With manganese(IV) oxide; In dichloromethane;

DOI:10.1021/jo701656z

upstream raw materials:

(tert-butyldimethylsilyl)acetylene

3,4,5-trimethoxy-benzaldehyde

Downstream raw materials:

3-(t-butyldimethylsilyl)-1-(3,4,5-trimethoxyphenyl)propynone