Technology Process of benzyl (2S,3R)-2-benzyl-3,4-dihydroxybutanoate
There total 3 articles about benzyl (2S,3R)-2-benzyl-3,4-dihydroxybutanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95 percent / toluene-p-sulfonic acid monohydrate / toluene / Heating
2: 1.) lithium diisopropylamide / 1) hexane, THF, -78 deg C, 1 h; 2) THF, hexane, -78 deg C, 1 h, -50 deg C, 5 h
3: 1.) boran, methyl sulfide, 2.) NaBH4 / 1) THF, 1 h; 2) THF, 30 min, room temperature
With
sodium tetrahydroborate; dimethylsulfide; borane; toluene-4-sulfonic acid; lithium diisopropyl amide;
In
toluene;
DOI:10.1039/P19950002877
- Guidance literature:
-
With
sodium tetrahydroborate; dimethylsulfide; borane;
Yield given. Multistep reaction;
1) THF, 1 h; 2) THF, 30 min, room temperature;
DOI:10.1039/P19950002877
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) lithium diisopropylamide / 1) hexane, THF, -78 deg C, 1 h; 2) THF, hexane, -78 deg C, 1 h, -50 deg C, 5 h
2: 1.) boran, methyl sulfide, 2.) NaBH4 / 1) THF, 1 h; 2) THF, 30 min, room temperature
With
sodium tetrahydroborate; dimethylsulfide; borane; lithium diisopropyl amide;
DOI:10.1039/P19950002877
