acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride

Base Information

• Chemical Name: acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride
• CAS No.: 886203-20-9
• Molecular Formula: C₁₄H₁₅NO₆S
• Molecular Weight: 325.342
• Mol file: 886203-20-9.mol

Synonyms:acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride

Chemical Property of acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride

There total 1 articles about acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tosyl-L-glutamic acid (4816-80-2) + acetyl chloride (75-36-5) → acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride (886203-20-9)

Guidance literature:

DOI:10.1039/jr9400000706

Reference yield:

acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride (886203-20-9) → 1-(4'-methylbenzenesulfonyl)-5-oxopyrrolidine-2-carboxylic acid (21957-65-3)

Guidance literature:

With 1,4-dioxane;

DOI:10.1039/jr9400000706

Reference yield:

acetic acid-[5-oxo-1-(toluene-4-sulfonyl)-L-proline]-anhydride (886203-20-9) → 5-oxo-1-(toluene-4-sulfonyl)-L-proline amide (104398-41-6)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous dioxane

2: diethyl ether; PCl₅

3: CHCl₃; NH₃

With 1,4-dioxane; diethyl ether; chloroform; phosphorus pentachloride; ammonia;

DOI:10.1039/jr9400000706

upstream raw materials:

N-tosyl-L-glutamic acid

acetyl chloride

Downstream raw materials:

1-(4'-methylbenzenesulfonyl)-5-oxopyrrolidine-2-carboxylic acid

5-oxo-1-(toluene-4-sulfonyl)-L-proline amide

5-oxo-1-(toluene-4-sulfonyl)-L-prolyl chloride