Benzoic acid pyridin-4-ylmethylene-hydrazide

Base Information

• Chemical Name: Benzoic acid pyridin-4-ylmethylene-hydrazide
• CAS No.: 1507-93-3
• Molecular Formula: C13H11 N3 O
• Molecular Weight: 225.25
• European Community (EC) Number: 660-342-7
• NSC Number: 213592
• DSSTox Substance ID: DTXSID30425929
• ChEMBL ID: CHEMBL3209317
• Mol file: 1507-93-3.mol

Synonyms:Benzoic acid pyridin-4-ylmethylene-hydrazide;MLS000551211;SMR000174426;1507-93-3;PhCON2 INH deri;cid_310118;CHEMBL3209317;BDBM46471;DTXSID30425929;IDBRDJFOFNLZRV-XNTDXEJSSA-N;HMS1678L16;Isonicotinaldehyde benzoyl hydrazone;N-(4-pyridylmethyleneamino)benzamide;NSC213592;STK215203;AKOS000361328;NSC-213592;N-(pyridin-4-ylmethylideneamino)benzamide;N-[(E)-4-pyridylmethyleneamino]benzamide;Benzohydrazide, N2-(4-pyridylmethylene)-;Benzoic acid, (4-pyridylmethylene)hydrazide;BENZOIC (4-PYRIDYLMETHYLENE)HYDRAZIDE;N'-[(E)-pyridin-4-ylmethylidene]benzohydrazide;N'-[(E)-4-Pyridinylmethylidene]benzohydrazide #;SR-01000361092;SR-01000361092-1;N'-[(E)-(PYRIDIN-4-YL)METHYLIDENE]BENZOHYDRAZIDE

Chemical Property of Benzoic acid pyridin-4-ylmethylene-hydrazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.14g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 225.090211983
• Heavy Atom Count: 17
• Complexity: 266

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NN=CC2=CC=NC=C2
• Isomeric SMILES: C1=CC=C(C=C1)C(=O)N/N=C/C2=CC=NC=C2

Technology Process of Benzoic acid pyridin-4-ylmethylene-hydrazide

There total 5 articles about Benzoic acid pyridin-4-ylmethylene-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

pyridine-4-carbaldehyde (872-85-5) + benzoic acid hydrazide (613-94-5) → C13H11N3O (1507-93-3)

Guidance literature:

In ethanol; Reflux;

DOI:10.1016/j.bmc.2015.04.040

Reference yield: 80.0%

pyridine-4-carbaldehyde (872-85-5) + benzoic acid hydrazide (613-94-5) → benzoic acid-([4]pyridylmethylene-hydrazide) (1507-93-3)

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃; for 0.5h;

DOI:10.1016/S0223-5234(00)00120-3

Reference yield:

benzoic acid (65-85-0,8013-63-6) → C13H11N3O (1507-93-3)

Guidance literature:

Multi-step reaction with 3 steps

1: Amberlyst-15

2: hydrazine hydrate / ethanol / 3 h / Reflux

3: ethanol / Reflux

With hydrazine hydrate; In ethanol;

DOI:10.1016/j.bmc.2015.04.040

upstream raw materials:

pyridine-4-carbaldehyde

benzoic acid hydrazide

benzoic acid

benzoic acid ethyl ester

Downstream raw materials:

1-chloro-1-phenyl-4-(4-pyridyl)-2,3-diazabutadiene hydrochloride

4-(5-phenyl-1,3,4-oxadiazol-2-yl)pyridine

(S)-N'-[1-(pyridin-4-yl)but-3-enyl]benzohydrazide

(R)-N'-[1-(pyridin-4-yl)but-3-enyl]benzohydrazide