Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid

Base Information

• Chemical Name: Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid
• CAS No.: 141020-19-1
• Molecular Formula: C₂₁H₃₁NO₁₀
• Molecular Weight: 457.478
• Mol file: 141020-19-1.mol

Synonyms:Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid

Chemical Property of Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid

There total 10 articles about Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

Benzyl-O-(2,3,6-tri-O-benzoyl-4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-4,6-di-O-acetyl-2-desoxy-α-D-galactopyranosid (141020-18-0) → Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid (141020-19-1)

Guidance literature:

With sodium methylate; In methanol; for 12h;

Reference yield:

methyl 2,3,6-tri-O-benzoyl-α-D-galactopyranoside (3601-36-3,6344-46-3) → Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid (141020-19-1)

Guidance literature:

Multi-step reaction with 7 steps

1: 84 percent / pyridine / CH₂Cl₂ / 48 h / Ambient temperature

2: 94 percent / Bu3SnH, α,α'-azoisobutyronitrile / toluene / 4 h / Heating

3: 94 percent / iodotrimethylsilane / toluene / 3 h / Ambient temperature

4: 1.) Hg(CN)2, molecular sieves 4 Angstroem / 1.) dichloromethane, 1 h, 2.) 10 deg C, 5 h

5: 60 percent aq. acetic acid / 3 h / 40 °C

6: pyridine / 24 h

7: 94 percent / 0.1 N methanolic NaOMe / methanol / 12 h

With pyridine; trimethylsilyl iodide; 4 A molecular sieve; azobisisobutyronitrile; tri-n-butyl-tin hydride; sodium methylate; mercury(II) cyanide; acetic acid; In methanol; dichloromethane; toluene;

Reference yield:

Methyl-2,3,6-tri-O-benzoyl-4-desoxy-α-D-xylo-hexopyranosid (19488-41-6) → Benzyl-O-(4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-2-desoxy-α-D-galactopyranosid (141020-19-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 94 percent / iodotrimethylsilane / toluene / 3 h / Ambient temperature

2: 1.) Hg(CN)2, molecular sieves 4 Angstroem / 1.) dichloromethane, 1 h, 2.) 10 deg C, 5 h

3: 60 percent aq. acetic acid / 3 h / 40 °C

4: pyridine / 24 h

5: 94 percent / 0.1 N methanolic NaOMe / methanol / 12 h

With pyridine; trimethylsilyl iodide; 4 A molecular sieve; sodium methylate; mercury(II) cyanide; acetic acid; In methanol; toluene;

upstream raw materials:

Benzyl-O-(2,3,6-tri-O-benzoyl-4-desoxy-β-D-xylo-hexopyranosyl)-(1->3)-2-acetamido-4,6-di-O-acetyl-2-desoxy-α-D-galactopyranosid

methyl 2,3,6-tri-O-benzoyl-α-D-galactopyranoside

Methyl-2,3,6-tri-O-benzoyl-4-desoxy-α-D-xylo-hexopyranosid

2,3,6-Tri-O-benzoyl-4-desoxy-α-D-xylo-hexopyranosyliodid