19488-41-6

Basic information

• Product Name: Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-a-D-glucopyranoside
• Synonyms: Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-a-D-glucopyranoside;Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-α-D-glucopyranoside
• CAS NO: 19488-41-6
• Molecular Formula: C₂₈H₂₆O₈
• Molecular Weight: 490.50124
• Product Categories: Aromatics;Carbohydrates & Derivatives;Heterocycles
• Mol File: 19488-41-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 609.596°C at 760 mmHg
• Flash Point: 259.509°C
• Appearance: /
• Density: 1.302g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate, Methanol
• CAS DataBase Reference: Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-a-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-a-D-glucopyranoside(19488-41-6)
• EPA Substance Registry System: Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-a-D-glucopyranoside(19488-41-6)

Safety Data

• Hazardous Substances Data: 19488-41-6(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Methyl 2,3,6-Tri-O-benzoyl-4-deoxy-a-D-glucopyranoside can be used as a molecule for studying the substrate specificity of certain transferase enzymes involved in glycoprotein biosynthesis. It has also been used to investigate the epitope binding of particular murine monoclonal antibodies.

InChI:InChI=1/C28H26O8/c1-32-28-24(36-27(31)21-15-9-4-10-16-21)23(35-26(30)20-13-7-3-8-14-20)17-22(34-28)18-33-25(29)19-11-5-2-6-12-19/h2-16,22-24,28H,17-18H2,1H3/t22?,23-,24-,28-/m0/s1

Upstream product

• 79233-81-1 methyl 2,3,6-tri-O-benzoyl-4-O-(imidazolylthiocarbonyl)-α-D-glucopyranoside 
• 3601-36-3 methyl 2,3,6-tri-O-benzoyl-α-D-galactopyranoside 
• 118868-79-4 methyl 4-S-acetyl-2,3,6-tri-O-benzoyl-4-thio-α-D-galactopyranoside 
• 688-73-3 tri-n-butyl-tin hydride 
• 4137-34-2 methyl 2,3,6-tri-O-benzoyl-4-O-methylsulphonyl-α-D-galactopyranoside 
• 98-88-4 benzoyl chloride 
• 57784-06-2 methyl 2,3,6-tri-O-benzoyl-α-D-glucopyranoside 
• 264610-67-5 C₃₅H₃₀O₁₀S 
• 149832-00-8 C₃₀H₂₈O₉S₂ 
• 79233-80-0 methyl 2,3,6-tri-O-benzoyl-4-O-(imidazol-1-ylthiocarbonyl)-α-D-galactopyranoside 
• 107-13-1 acrylonitrile 
• 141020-13-5 Methyl-2,3,6-tri-O-benzoyl-4-O-phenoxythiocarbonyl-α-D-galactopyranosid 
• 124314-29-0 methyl 2,3,6-tri-O-benzoyl-4-deoxy-β-D-xylo-hexopyranoside 
• 23487-07-2 methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-iodo-α-D-gluco-pyranoside 

Downstream Products

• 13241-00-4 methyl 4-deoxy-α-D-xylo-hexopyranoside 
• 122714-12-9 2,3,6-tri-O-benzoyl-4-deoxy-α-D-xylo-hexopyranosyl chloride 
• 141020-15-7 2,3,6-Tri-O-benzoyl-4-desoxy-α-D-xylo-hexopyranosyliodid 
• 13264-03-4 Methyl 2,3,6-tri-O-acetyl-4-deoxy-α-D-glucopyranoside 
• 849132-36-1 phenyl 2,3,6-tri-O-acetyl-4-deoxy-1-thio-β-D-xylo-hexoside 
• 149831-88-9 2-(N-Phenylsulfonylindol-3-yl)-ethyl 4-Deoxy-β-D-glucopyranoside 
• 149850-28-2 C₂₇H₂₃BrO₇ 
• 149831-91-4 2-(N-Phenylsulfonylindol-3-yl)-ethyl 2,3-Di-O-benzyl-4-deoxy-β-D-glucopyranoside 
• 149831-89-0 2-(N-(phenylsulfonyl)indol-3-yl)ethyl 4-deoxy-6-(O-tert-butyldimethylsilyl)-β-D-glucopyranoside 
• 149831-87-8 2-(N-(phenylsulfonyl)indol-3-yl)ethyl 2,3,6-tri-O-benzoyl-4-deoxy-β-D-glucopyranoside 
• 149831-90-3 2-(N-(phenylsulfonyl)indol-3-yl)ethyl 2,3-di-O-benzyl-4-deoxy-6-(O-tert-butyldimethylsilyl)-β-D-glucopyranoside 
• 149831-92-5 2-(N-(phenylsulfonyl)indol-3-yl)ethyl 2,3-di-O-benzyl-4-deoxy-6-O-(5-phthalimidopentyl)-β-D-glucopyranoside 
• 141020-14-6 1-O-Acetyl-2,3,6-tri-O-benzoyl-4-desoxy-α-D-xylo-hexopyranose 
• 114942-44-8 2,4-dinitrophenyl-2,3,6-tri-O-acetyl-4-deoxy-β-D-xylo-hexopyranoside 

Relevant articles and documents

A One-Pot Method for Removal of Thioacetyl Group via Desulfurization under Ultraviolet Light to Synthesize Deoxyglycosides

We herein developed an efficient method for removing thioacetyl to synthesize acylated deoxy glycosides in a one-pot reaction, where the thioacetyl was selectively deacetylated by hydrazine hydrate in DMF within 2-5 min at room temperature, followed by de

Hydrolytic activity of α-galactosidases against deoxy derivatives of p- nitrophenyl α-D-galactopyranoside

The four possible monodeoxy derivatives of p-nitrophenyl (PNP) α-D- galactopyranoside were synthesized, and hydrolytic activities of the α- galactosidase of green coffee bean, Mortierella vinacea and Aspergillus niger against them were elucidated. The 2- and 6-deoxy substrates were hydrolyzed by the enzymes from green coffee bean and M. vinacea, while they scarcely acted on the 3- and 4-deoxy compounds. On the other hand, A. niger α- galactosidase hydrolyzed only the 2-deoxy compound in these deoxy substrates, and the activity was very high. These results indicate that the presence of two hydroxyl groups (OH-3 and -4) is essential for the compounds to act as substrates for the enzymes of green coffee bean and M. vinacea, while the three hydroxyl groups (OH-3, -4, and -6) are necessary for the activity of the A. niger enzyme. The kinetic parameters (K(m) and V(max)) of the enzymes for the hydrolysis of PNP α-D-galactopyranoside and its deoxy derivatives were obtained from kinetic studies. (C) 2000 Elsevier Science Ltd.

NON-PEPTIDE PEPTIDOMIMETICS

Compounds are provided which are crossreactive with peptides such as those which bind G-protein-linked receptors, together with preparative and therapeutic methods therefor. The compounds have the general structure: STR1 wherein at least one of R 1, R 2, R. sub.3, R. sub.4, or R 5 comprises a functional group which is chemically similar to that found in the peptide of interest.