N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide

Base Information

• Chemical Name: N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide
• CAS No.: 128844-34-8
• Molecular Formula: C₂₄H₂₇NO₄
• Molecular Weight: 393.483
• Mol file: 128844-34-8.mol

Synonyms:N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide

Chemical Property of N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide

There total 2 articles about N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-(4-tert-butylphenyl)maleimide (1084-26-0) + 1,4-dimethoxy-2,3-bis(bromomethyl)benzene (19164-83-1) → N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide (128844-34-8)

Guidance literature:

With sodium iodide; In N,N-dimethyl-formamide;

DOI:10.1021/jo00303a008

Reference yield:

4-tert-Butylaniline (769-92-6) → N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide (128844-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: entsp. Lit_.zitat

2: 62 percent / NaI / dimethylformamide

With sodium iodide; In N,N-dimethyl-formamide;

DOI:10.1021/jo00303a008

Reference yield:

N-(4-tert-butylphenyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2,3-naphthalenedicarboximide (128844-34-8) → N-(4-tert-butylphenyl)-1,4-dioxo-6,7-naphthalenedicarboximide (128844-36-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NBS, benzoyl peroxide 2.) NEt₃ / 1.) CCl₄, reflux 2.) RT

2: 49 percent / Ceric ammonium nitrate / acetonitrile; H₂O / 0.75 h

With N-Bromosuccinimide; Perbenzoic acid; ammonium cerium(IV) nitrate; triethylamine; In water; acetonitrile;

DOI:10.1021/jo00303a008

upstream raw materials:

N-(4-tert-butylphenyl)maleimide

1,4-dimethoxy-2,3-bis(bromomethyl)benzene

4-tert-Butylaniline

Downstream raw materials:

N-(4-tert-butylphenyl)-5,8-dimethoxy-2,3-naphthalenedicarboximide

N-(4-tert-butylphenyl)-1,4-dioxo-6,7-naphthalenedicarboximide