(1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester

Base Information

• Chemical Name: (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester
• CAS No.: 108885-08-1
• Molecular Formula: C₁₆H₂₀O₄S
• Molecular Weight: 308.398
• Mol file: 108885-08-1.mol

Synonyms:(1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester

Chemical Property of (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester

There total 3 articles about (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

Camphorsulfonyl chloride (21286-54-4) + phenol (108-95-2,27073-41-2) → (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester (108885-08-1)

Guidance literature:

With pyridine; at 0 ℃;

DOI:10.1039/a806867d

Reference yield:

(1S)-10-camphorsulfonic acid (3144-16-9,61380-66-3) → (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester (108885-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 59 percent / PCl₅

2: 78 percent / pyridine

With pyridine; phosphorus pentachloride;

Reference yield:

((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride (6994-93-0) + phenol (108-95-2,27073-41-2) → (+/-)-2-oxo-bornane-10-sulfonic acid phenyl ester (108885-08-1)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

Camphorsulfonyl chloride

phenol

(1S)-10-camphorsulfonic acid

((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride

Downstream raw materials:

(1S,2R)-(7,7-dimethyl-2-hydroxybicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester

(1R,2R)-(7,7-dimethyl-2-exo-benzylselenylbicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester

[(1S,2S,4R,6R,7S)-10,10-Dimethyl-4-((1R,2R)-2-phenyl-cyclopropyl)-3,5-dioxa-tricyclo[5.2.1.0^2,6]dec-1-yl]-methanesulfonic acid phenyl ester

[(1S,2S,4R,6R,7S)-10,10-Dimethyl-4-((1R,2R)-2-propyl-cyclopropyl)-3,5-dioxa-tricyclo[5.2.1.0^2,6]dec-1-yl]-methanesulfonic acid phenyl ester