2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene]

Base Information

• Chemical Name: 2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene]
• CAS No.: 932371-01-2
• Molecular Formula: C₁₉H₁₄N₂O₂
• Molecular Weight: 302.332
• Mol file: 932371-01-2.mol

Synonyms:2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene]

Chemical Property of 2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene]

There total 1 articles about 2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-fluoren-9-ylidene-malononitrile (1989-32-8) + 2,5-dihydro-2,2-dimethoxy-5-methyl-5-(p-methoxyphenyl)-1,3,4-oxadiazole (845618-72-6) → 2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene] (932371-01-2) + 1-(4-methoxyphenyl)ethanone (100-06-1)

Guidance literature:

In benzene; at 50 ℃; for 24h;

DOI:10.1021/ol063021s

Reference yield:

2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene] (932371-01-2) + 4-methyl-benzaldehyde (104-87-0) → C27H22N2O3

Guidance literature:

In benzene-d6; at 25 ℃; Kinetics;

DOI:10.1021/ol063021s

Reference yield:

2,2-dimethoxy-3,3-dicyanospiro[cyclopropane-1,9'-[9H]fluorene] (932371-01-2) + 4-fluorobenzaldehyde (459-57-4) → C26H19FN2O3

Guidance literature:

In benzene-d6; at 25 ℃; Kinetics;

DOI:10.1021/ol063021s

upstream raw materials:

2-fluoren-9-ylidene-malononitrile

2,5-dihydro-2,2-dimethoxy-5-methyl-5-(p-methoxyphenyl)-1,3,4-oxadiazole