Technology Process of C45H46F6N2O9
There total 5 articles about C45H46F6N2O9 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
calcium sulfate; scandium tris(trifluoromethanesulfonate);
In
1,2-dichloro-ethane;
at -30 - 0 ℃;
for 3h;
enantioselective reaction;
DOI:10.1002/anie.201308016
- Guidance literature:
-
Multi-step reaction with 2 steps
1: magnesium iodide diethyletherate / diethyl ether; tetrahydrofuran / 5 h / 0 - 50 °C
2: scandium tris(trifluoromethanesulfonate); calcium sulfate / 1,2-dichloro-ethane / 3 h / -30 - 0 °C
With
calcium sulfate; magnesium iodide diethyletherate; scandium tris(trifluoromethanesulfonate);
In
tetrahydrofuran; diethyl ether; 1,2-dichloro-ethane;
DOI:10.1002/anie.201308016
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C
1.2: 0.33 h / -78 °C
1.3: -78 - 20 °C
2.1: trimethylsilyl trifluoromethanesulfonate; calcium sulfate / 1,2-dichloro-ethane / 19 h / -30 - 30 °C / Inert atmosphere
3.1: magnesium iodide diethyletherate / diethyl ether; tetrahydrofuran / 5 h / 0 - 50 °C
4.1: scandium tris(trifluoromethanesulfonate); calcium sulfate / 1,2-dichloro-ethane / 3 h / -30 - 0 °C
With
calcium sulfate; magnesium iodide diethyletherate; trimethylsilyl trifluoromethanesulfonate; scandium tris(trifluoromethanesulfonate); lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; 1,2-dichloro-ethane;
DOI:10.1002/anie.201308016
